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Abhijit Mazumdar
Researcher at University of Texas MD Anderson Cancer Center
Publications - 59
Citations - 3327
Abhijit Mazumdar is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 28, co-authored 48 publications receiving 2937 citations. Previous affiliations of Abhijit Mazumdar include Centre national de la recherche scientifique & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor
Abhijit Mazumdar,Rui-An Wang,Sandip K. Mishra,Liana Adam,Rozita Bagheri-Yarmand,Mahitosh Mandal,Ratna K. Vadlamudi,Rakesh Kumar +7 more
TL;DR: Results identify ER-mediated transcription as a nuclear target of MTA1 and indicate that HDAC complexes associated with the MTA1 corepressor may mediate ER transcriptional repression by HRG.
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Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Zachary C. Hartman,Graham M. Poage,Petra den Hollander,Anna Tsimelzon,Jamal Hill,Nattapon Panupinthu,Yun Zhang,Abhijit Mazumdar,Susan G. Hilsenbeck,Gordon B. Mills,Powel H. Brown +10 more
TL;DR: A Cox multivariable analysis of patient specimens revealed that IL-6 and IL-8 expression predicted patient survival times, offering a rationale for dual inhibition of IL- 6/IL-8 signaling as a therapeutic strategy to improve outcomes for patients with TNBCs.
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A naturally occurring MTA1 variant sequesters oestrogen receptor-α in the cytoplasm
Rakesh Kumar,Rui An Wang,Abhijit Mazumdar,Amjad H. Talukder,Mahitosh Mandal,Zhibo Yang,Rozita Bagheri-Yarmand,Aysegul A. Sahin,Gabriel N. Hortobagyi,Liana Adam,Christopher J. Barnes,Ratna K. Vadlamudi +11 more
TL;DR: A naturally occurring short form of MTA1 (MTA1s) that contains a previously unknown sequence of 33 amino acids with an ER-binding motif, Leu-Arg-Ile-Leu- Leu (LRILL) that represents a mechanism for redirecting nuclear receptor signalling by nuclear exclusion.
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P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-α and promotes hyperplasia in mammary epithelium
TL;DR: A novel role for the Pak1–ER pathway in promoting hyperplasia in mammary epithelium is revealed and inhibition of Pak1 kinase activity by a dominant‐negative fragment or by short interference RNA markedly reduced the estrogen receptor‐α (ER) transactivation functions.
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Molecular Cloning and Characterization of PELP1, a Novel Human Coregulator of Estrogen Receptor α
Ratna K. Vadlamudi,Rui An Wang,Abhijit Mazumdar,Yoon Sok Kim,Jaekyoon Shin,Aysegul A. Sahin,Rakesh Kumar +6 more
TL;DR: It is suggested that PELP1 is a novel coregulator of ERα and may have a role in breast cancer tumorigenesis.