K
Klaus Pantel
Researcher at University of Hamburg
Publications - 566
Citations - 36666
Klaus Pantel is an academic researcher from University of Hamburg. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 90, co-authored 486 publications receiving 29848 citations.
Papers
More filters
Journal ArticleDOI
Comparison of the HER2, estrogen and progesterone receptor expression profile of primary tumor, metastases and circulating tumor cells in metastatic breast cancer patients.
Bahriye Aktas,Sabine Kasimir-Bauer,Volkmar Müller,Wolfgang Janni,Tanja Fehm,D. Wallwiener,Klaus Pantel,Mitra Tewes +7 more
TL;DR: It is demonstrated that the molecular detection of HER2 overexpression in CTC is predictive of the HER2 status on metastases, and detailed analysis of ER and PR expression rates in tissue samples and CTCs may provide useful information for making treatment decisions.
Journal ArticleDOI
Molecular mechanisms of metastasis
Dave S.B. Hoon,Minoru Kitago,Joseph Kim,Takuji Mori,Adriano Piris,Katherine Szyfelbein,Martin C. Mihm,S. David Nathanson,Timothy P. Padera,Ann F. Chambers,Sharon A. Vantyghem,Ian C. MacDonald,Steven C. Shivers,Marwan Alsarraj,Douglas S. Reintgen,Bernward Passlick,Wulf Sienel,Klaus Pantel +17 more
TL;DR: The symposium covered new aspects and important questions related to the events of metastasis in both humans and animals and the hope is that further unraveling of the direct and indirect molecular events of lymphatic metastasis will lead to new approaches in developing effective therapeutics.
Journal ArticleDOI
Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.
Menelaos Zafrakas,Basil C. Tarlatzis,Thomas Streichert,Fotios Pournaropoulos,Ute Wölfle,Serge J. Smeets,Britta Wittek,Grigorios Grimbizis,Ruud H. Brakenhoff,Klaus Pantel,John N. Bontis,Cagatay Günes +11 more
TL;DR: Data suggest that advanced ovarian endometriosis represents a highly differentiated tissue with minimal or no malignant potential, suggesting a high degree of differentiation.
Journal ArticleDOI
Limited prognostic value of preoperative circulating tumor cells for early biochemical recurrence in patients with localized prostate cancer
Christian Meyer,Klaus Pantel,Pierre Tennstedt,Petra Stroelin,Thorsten Schlomm,Hans Heinzer,Sabine Riethdorf,Thomas Steuber +7 more
TL;DR: Using the CellSearch system, CTCs infrequently detected in patients with localized tumors before RP did not correlate significantly with PSA, disease characteristics, or the development of BCR, however, larger cohorts with extended follow-up are needed.
Journal ArticleDOI
Current status in human breast cancer micrometastasis.
TL;DR: Understanding tumor dormancy and identifying metastatic stem cells might result in the development of new concepts for antimetastatic therapies, and research on disseminated tumor cells/circulating tumor cells will help to identify novel targets for biological therapies aimed at preventing metastatic relapse and to monitor the efficacy of these therapies.