K
Klaus Pantel
Researcher at University of Hamburg
Publications - 566
Citations - 36666
Klaus Pantel is an academic researcher from University of Hamburg. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 90, co-authored 486 publications receiving 29848 citations.
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Journal ArticleDOI
Prospective Comparison of the Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of a Single Patient's Cohort With Esophageal Cancer
Leonie Konczalla,Tarik Ghadban,Katharina E. Effenberger,Anna Wöstemeier,Sabine Riethdorf,Faik G. Uzunoglu,Jakob R. Izbicki,Klaus Pantel,Maximilian Bockhorn,Matthias Reeh +9 more
TL;DR: In this early disease stage, only the CTC status was an independent, prognostic marker suitable and easy to use for clinical staging of patients with EC.
Journal ArticleDOI
Potential of circulating tumor cells as blood-based biomarkers in cancer liquid biopsy
Thomas Schlange,Klaus Pantel +1 more
TL;DR: In the future, circulating tumor cells may dramatically improve the authors' ability to monitor malignancies and indicate whether or not a treatment may work, arguing for complementary roles of conventional and liquid biopsies.
Journal ArticleDOI
Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma.
Sabine Riethdorf,Lina Hildebrandt,Lucie Heinzerling,Ellen Heitzer,Nicole Fischer,Sonja Bergmann,Oliver Mauermann,Julie Waldispühl-Geigl,Cornelia Coith,Gerhard Schön,Sven Peine,Gerold Schuler,Michael R. Speicher,Ingrid Moll,Klaus Pantel +14 more
TL;DR: The presence of C TCs is a prognostic factor of impaired clinical outcome, with the potential to monitor the progression of the disease in real time, and molecular characterization of CTCs might provide new insights into the biology of MCC.
Journal ArticleDOI
Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Natalia Bednarz-Knoll,Paulina Nastały,Anna J. Żaczek,MaÅ Gorzata Stoupiec,Sabine Riethdorf,Harriet Wikman,Volkmar Müller,Jarosław Skokowski,Jolanta Szade,Aleksandra Sejda,Marzena Wełnicka-Jaśkiewicz,Klaus Pantel +11 more
TL;DR: AlDH1 expression in tumor-associated stromal cells indicates reduced BrCa progression, possibly via RA secretion.
Journal ArticleDOI
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Desiree Loreth,Moritz Schuette,Jenny Zinke,Malte Mohme,Andras Piffko,Svenja Schneegans,Julia T. Stadler,Melanie Janning,Melanie Janning,Melanie Janning,Sonja Loges,Sonja Loges,Sonja Loges,Simon A. Joosse,Katrin Lamszus,Manfred Westphal,Volkmar Müller,Markus Glatzel,Jakob Matschke,Christoffer Gebhardt,Stefan W. Schneider,Iwona Belczacka,Beate Volkmer,Rüdiger Greinert,Marie-Laure Yaspo,Patrick N. Harter,Klaus Pantel,Harriet Wikman +27 more
TL;DR: It is shown that a size-based microfluidic approach in combination with a semi-automated cell recognition system are well suited for CTC detection in BM patients and allow further characterization of tumor cells potentially derived from BM.