K
Kong Jie Kah
Researcher at Massachusetts Institute of Technology
Publications - 2
Citations - 872
Kong Jie Kah is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Autocrine signalling & Wnt signaling pathway. The author has an hindex of 1, co-authored 2 publications receiving 763 citations.
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Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.
Christina Scheel,Elinor Ng Eaton,Sophia Hsin-Jung Li,Christine L. Chaffer,Ferenc Reinhardt,Kong Jie Kah,George W. Bell,Wenjun Guo,Jeffrey S. Rubin,Andrea L. Richardson,Robert A. Weinberg +10 more
TL;DR: In this article, the authors describe three signaling pathways, involving transforming growth factor (TGF)-β and canonical and noncanonical Wnt signaling, that collaborate to induce activation of the EMT program and thereafter function in an autocrine fashion to maintain the resulting mesenchymal state.
Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast
Christina Scheel,Elinor Ng Eaton,Sophia Hsin-Jung Li,Christine L. Chaffer,Ferenc Reinhardt,Kong Jie Kah,George W. Bell,Wenjun Guo,Jeffrey S. Rubin,Andrea L. Richardson,Robert A. Weinberg +10 more
TL;DR: Three signaling pathways are described, involving transforming growth factor (TGF)-β and canonical and noncanonical Wnt signaling, that collaborate to induce activation of the EMT program and thereafter function in an autocrine fashion to maintain the resulting mesenchymal state.