K
Kory R. Johnson
Researcher at National Institutes of Health
Publications - 118
Citations - 5559
Kory R. Johnson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Medicine & Induced pluripotent stem cell. The author has an hindex of 29, co-authored 99 publications receiving 4125 citations. Previous affiliations of Kory R. Johnson include University of Southern California & United States Department of Health and Human Services.
Papers
More filters
Journal ArticleDOI
Tumor necrosis factor identified in multiple sclerosis brain.
TL;DR: The presence of TNF in MS lesions suggests a significant role for cytokines and the immune response in disease progression and is not made in Alzheimer's disease or normal brain tissue.
Journal ArticleDOI
Human endogenous retrovirus-K contributes to motor neuron disease
Wenxue Li,Myoung Hwa Lee,Lisa J. Henderson,Richa Tyagi,Muzna Bachani,Joseph P. Steiner,Emilie Campanac,Dax A. Hoffman,Gloria von Geldern,Kory R. Johnson,Dragan Maric,H. Douglas Morris,Margaret R. Lentz,Katherine Pak,Andrew L. Mammen,Lyle W. Ostrow,Jeffrey D. Rothstein,Avindra Nath +17 more
TL;DR: It is shown that HERV-K is activated in a subpopulation of patients with sporadic amyotrophic lateral sclerosis (ALS) and that its envelope (env) protein may contribute to neurodegeneration and disease pathogenesis.
Journal ArticleDOI
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.
Hetal Pandya,Michael J. Shen,David M. Ichikawa,Andrea B. Sedlock,Yong Choi,Kory R. Johnson,Gloria Kim,Mason A Brown,Abdel G. Elkahloun,Dragan Maric,Colin L. Sweeney,Selamawit Gossa,Harry L. Malech,Dorian B. McGavern,John K. Park +14 more
TL;DR: The differentiation of human induced pluripotent stem cells (iPSC) into microglia-like cells by exposure to defined factors and co-culture with astrocytes is reported, which have the phenotype, gene expression profile and functional properties of brain-isolatedmicroglia.
Journal ArticleDOI
Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior.
Anupama Sathyamurthy,Kory R. Johnson,Kaya J.E. Matson,Courtney I. Dobrott,Li Li,Anna R. Ryba,Tzipporah B. Bergman,Michael C. Kelly,Matthew W. Kelley,Ariel J. Levine +9 more
TL;DR: This work used massively parallel single nucleus RNA sequencing (snRNA-seq) to create an atlas of the adult mouse lumbar spinal cord and identified and molecularly characterized 43 neuronal populations that were active following a sensory and a motor behavior.
Journal ArticleDOI
Identification of Dynamically Regulated microRNA and mRNA Networks in Developing Oligodendrocytes
Pierre Lau,Jonathan D. Verrier,Joseph A. Nielsen,Kory R. Johnson,Lucia Notterpek,Lynn D. Hudson +5 more
TL;DR: It is demonstrated that miR-9 interacts with the 3′ untranslated region of PMP22 and downregulates its expression, which supports models in which miRNAs can act as guardians of the transcriptome.