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Kotatsu Bito

Researcher at Kao Corporation

Publications -  12
Citations -  173

Kotatsu Bito is an academic researcher from Kao Corporation. The author has contributed to research in topics: Raman scattering & Stratum corneum. The author has an hindex of 7, co-authored 9 publications receiving 148 citations. Previous affiliations of Kotatsu Bito include University of Tokyo.

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The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes.

TL;DR: The thermotropic phase behavior and the mixing properties of the SC lipid mixtures were shown to strongly depend on the chain length and chain length distribution of FFAs, while hydration enhanced the phase separation.
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Infrared photodissociation spectroscopy of protonated ammonia cluster ions, NH4+(NH3)n (n=5-8), by using infrared free electron laser.

TL;DR: Analyses by the density functional theory (DFT) show that the spectral features observed can be assigned to the nu(2) vibrational mode of the NH(3) molecules in NH(4) (+)(NH(3))(n).
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Protein Secondary Structure Imaging with Ultrabroadband Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Microspectroscopy

TL;DR: A multilayered structure in the human hair cortex is found using the new imaging technique, CARS peak-shift mapping, which clearly visualizes the treatment induced changes in protein secondary structures and their spatial distributions.
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In vivo evaluation of lateral lipid chain packing in human stratum corneum

TL;DR: The matrix of intercellular lipids of stratum corneum plays an important role in the barrier function of SC and it is important to understand the structure of the ICL matrix for dermatology and cosmetic science.
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Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype.

TL;DR: Results indicate that the penetrated pCer contributes to shift the ceramide profile from an AD to a healthy skin phenotype, providing a deep insight into the pathogenesis of AD as a ceramide-deficient disease.