T
Thomas Arnesen
Researcher at University of Bergen
Publications - 122
Citations - 6885
Thomas Arnesen is an academic researcher from University of Bergen. The author has contributed to research in topics: Acetylation & Acetyltransferase. The author has an hindex of 42, co-authored 106 publications receiving 5567 citations. Previous affiliations of Thomas Arnesen include Haukeland University Hospital.
Papers
More filters
Journal ArticleDOI
The world of protein acetylation
TL;DR: This review gives a general overview of protein acetylation and the respective acetyltransferases, and focuses on the regulation of metabolic processes and physiological consequences that come along with proteinacetylation.
Journal ArticleDOI
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
Thomas Arnesen,Petra Van Damme,Bogdan Polevoda,Kenny Helsens,Rune Evjenth,Niklaas Colaert,Jan Erik Varhaug,Joël Vandekerckhove,Johan R. Lillehaug,Fred Sherman,Kris Gevaert +10 more
TL;DR: Although the COmbined FRActional DIagonal Chromatography technology was used to determine the N-terminal acetylation status of 742 human and yeast protein N termini, it was revealed that NatA from humans and yeast have identical or nearly identical specificities.
Journal ArticleDOI
Spotlight on protein N-terminal acetylation.
TL;DR: This review provides an overview of eukaryotic N-terminal acetyltransferases (NATs) and the impact of Nt-acetylation, and discusses other functions of known NATs and outline methods for studying NT- acetylation.
Journal ArticleDOI
Protein N-terminal acetyltransferases: when the start matters
TL;DR: How recent findings shed light on NATs as major protein regulators and key cellular players are discussed are discussed.
Journal ArticleDOI
Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency
Alan F. Rope,Kai Wang,Rune Evjenth,Jinchuan Xing,Jennifer J. Johnston,Jeffrey Swensen,Jeffrey Swensen,W. Evan Johnson,Barry Moore,Chad D. Huff,Lynne M. Bird,John C. Carey,John M. Opitz,Cathy A. Stevens,Tao Jiang,Christa Schank,Heidi D. Fain,Reid J. Robison,Brian Dalley,Steven S. Chin,Sarah T. South,Sarah T. South,Theodore J. Pysher,Lynn B. Jorde,Hakon Hakonarson,Johan R. Lillehaug,Leslie G. Biesecker,Mark Yandell,Thomas Arnesen,Thomas Arnesen,Gholson J. Lyon,Gholson J. Lyon +31 more
TL;DR: Evidence is provided of a human genetic disorder resulting from direct impairment of N-terminal acetylation, one of the most common protein modifications in humans, and the pathogenic mutation hNaa10p causes this disease.