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Kristen Rebecca Curtis
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 7
Citations - 1490
Kristen Rebecca Curtis is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Prostate cancer & Gene. The author has an hindex of 3, co-authored 7 publications receiving 1105 citations.
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Journal ArticleDOI
Organoid cultures derived from patients with advanced prostate cancer
Dong Gao,Ian Vela,Andrea Sboner,Phillip J. Iaquinta,Wouter R. Karthaus,Anuradha Gopalan,Catherine Dowling,Jackline Wanjala,Eva Undvall,Vivek K. Arora,John Wongvipat,Myriam Kossai,Sinan Ramazanoglu,Luendreo P Barboza,Wei Di,Zhen Cao,Qi Fan Zhang,Inna Sirota,Leili Ran,Theresa Y MacDonald,Himisha Beltran,Juan Miguel Mosquera,Karim Touijer,Peter T. Scardino,Vincent P. Laudone,Kristen Rebecca Curtis,Dana E. Rathkopf,Michael J. Morris,Michael J. Morris,Daniel C. Danila,Daniel C. Danila,Susan F. Slovin,Susan F. Slovin,Stephen B. Solomon,James A. Eastham,Ping Chi,Brett S. Carver,Mark A. Rubin,Howard I. Scher,Howard I. Scher,Hans Clevers,Charles L. Sawyers,Charles L. Sawyers,Yu Chen,Yu Chen +44 more
TL;DR: Using a 3D organoid system, this paper reported success in long-term culture of prostate cancer from biopsy specimens and circulating tumor cells, including TMPRSS2-ERG fusion, SPOP mutation, SPINK1 overexpression, and CHD1 loss.
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Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.
Wassim Abida,Joshua Armenia,Anuradha Gopalan,Ryan Brennan,Michael Walsh,David Barron,Daniel C. Danila,Dana E. Rathkopf,Michael J. Morris,Susan F. Slovin,Brigit McLaughlin,Kristen Rebecca Curtis,David M. Hyman,Jeremy C. Durack,Stephen B. Solomon,Maria E. Arcila,Ahmet Zehir,Aijazuddin Syed,Jianjiong Gao,Debyani Chakravarty,Hebert Alberto Vargas,Mark E. Robson,Joseph Vijai,Kenneth Offit,Mark T.A. Donoghue,Adam Abeshouse,Ritika Kundra,Zachary J. Heins,Alexander V Penson,Chris Harris,Barry S. Taylor,Marc Ladanyi,Diana Mandelker,Liying Zhang,Victor E. Reuter,Philip W. Kantoff,David B. Solit,Michael F. Berger,Charles L. Sawyers,Nikolaus Schultz,Howard I. Scher +40 more
TL;DR: The findings support the routine use of tumor and germline DNA profiling for patients with advanced prostate cancer, for the purpose of guiding enrollment in targeted clinical trials and counseling families at increased risk of malignancy.
Journal ArticleDOI
Brain metastases from prostate cancer: an 11-year analysis in the MRI era with emphasis on imaging characteristics, incidence, and prognosis.
Vaios Hatzoglou,Gita V. Patel,Michael J. Morris,Kristen Rebecca Curtis,Zhigang Zhang,Weiji Shi,Jason T. Huse,Marc K. Rosenblum,Andrei I. Holodny,Robert J. Young +9 more
TL;DR: The main objectives of this study were to evaluate the incidence, MRI characteristics, and prognosis of parenchymal brain metastases originating in prostate cancer.
Journal ArticleDOI
STEAP1 as a predictive biomarker for antibody-drug conjugate (ADC) activity in metastatic castration resistant prostate cancer (mCRPC).
Daniel C. Danila,Martin Fleisher,Jorge A. Carrasquillo,Houston Gilbert,Michael J. Morris,Lawrence P. Bellomo,Petrus J. Hendrikx,Edith Szafer-Glusman,Amrita Herkal,Chintan Patel,Nicole A. Schreiber,Kristen Rebecca Curtis,Daniel J. Maslyar,Vanessa Lemahieu,Bernard M. Fine,Michael Mamounas,Alexander Ungewickell,Mark R. Lackner,Howard I. Scher,Omar Kabbarah +19 more
TL;DR: In this paper, STEAP1 expression in tissue assayed by IHC, protein and mRNA expression levels in circulating tumor cells (CTC) and by 89Zr-l...
Journal ArticleDOI
Genomic characterization of primary and metastatic prostate cancer (PC) using a targeted next-generation sequencing assay.
Wassim Abida,Ryan Brennan,Joshua Armenia,Kristen Rebecca Curtis,Anuradha Gopalan,Maria E. Arcila,Daniel C. Danila,Dana E. Rathkopf,Michael J. Morris,Susan F. Slovin,David B. Solit,David M. Hyman,Jeremy C. Durack,Stephen B. Solomon,Victor E. Reuter,Barry S. Taylor,Michael F. Berger,Nikolaus Schultz,Howard I. Scher +18 more
TL;DR: Assessment of mutations and copy number alterations in primary and metastatic samples from untreated, hormone-treated and castration resistant pts and MSK-IMPACT, an exon capture-based sequencing assay performed in a CLIA-certified laboratory, identified somatic mutations and CNAs.