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Kristina Hettne
Researcher at Leiden University Medical Center
Publications - 67
Citations - 1636
Kristina Hettne is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Workflow & Metadata. The author has an hindex of 21, co-authored 64 publications receiving 1306 citations. Previous affiliations of Kristina Hettne include Leiden University & Maastricht University.
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Top 10 FAIR Data Software Things
Christopher Erdmann,Natasha Simons,Reid Otsuji,Stephanie G. Labou,Ryan Johnson,Guilherme P. Castelão,Bia Villas Boas,Anna-Lena Lamprecht,Carlos Martinez Ortiz,Leyla Garcia,Mateusz Kuzak,Paula Martinez,Liz Stokes,Tom Honeyman,Sharyn Wise,Josh Quan,Scott Peterson,Amy Neeser,Lena Karvovskaya,Otto Lange,Iza Witkowska,Jacques Flores,Fiona Bradley,Kristina Hettne,Peter Verhaar,B.A. Companjen,Laurents Sesink,Fieke Schoots,Erik Anthony Schultes,Rajaram Kaliyaperumal,Erzsébet Tóth-Czifra,Ricardo de Miranda Azevedo,Sanne Muurling,John Brown,Janice Chan,Niamh Quigley,Lisa Federer,Douglas Joubert,Allissa Dillman,Kenneth Wilkins,Ishwar Chandramouliswaran,Vivek Navale,Susan Wright,Silvia Di Giorgio,Mandela Fasemore,Konrad Förstner,Till Sauerwein,Eva Seidlmayer,Ilja Zeitlin,Susannah Bacon,Katie Hannan,Richard Ferrers,Keith Russell,Deidre Whitmore,Tim Dennis +54 more
Book ChapterDOI
Reusable FAIR Implementation Profiles as Accelerators of FAIR Convergence
Erik Anthony Schultes,Barbara Magagna,Kristina Hettne,Robert Pergl,Marek Suchánek,Tobias Kuhn +5 more
TL;DR: In this article, the concept of FAIR Implementation Profile (FIP) is proposed to capture the comprehensive set of implementation choices made at the discretion of individual communities of practice, and the collection of community-specific FIPs compose an online resource called the FIP Convergence Matrix which can be used to track the evolving landscape of fair implementations and inform optimisation around reuse and interoperation.
Journal ArticleDOI
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients.
Mirko Signorelli,Mitra Ebrahimpoor,Olga Veth,Kristina Hettne,Nisha Verwey,Raquel García-Rodríguez,Christa L Tanganyika-deWinter,Luz B Lopez Hernandez,Luz B Lopez Hernandez,Rosa Escobar Cedillo,Benjamín Gómez Díaz,Olafur T. Magnusson,Hailiang Mei,Roula Tsonaka,Annemieke Aartsma-Rus,Pietro Spitali +15 more
TL;DR: In this paper, the authors used RNA-sequencing to describe the pathophysiological changes in skeletal muscle of 3 dystrophic mouse models, and showed how dystonrophic changes in muscle are reflected in blood by analyzing paired muscle and blood samples.
Posted Content
The FAIR Funder pilot programme to make it easy for funders to require and for grantees to produce FAIR Data
Peter Wittenburg,Hana Pergl Sustkova,Annalisa Montesanti,Margreet Bloemers,S.H. de Waard,Mark A. Musen,John Graybeal,Kristina Hettne,Annika Jacobsen,Robert Pergl,Rob Hooft,Christine Staiger,Celia W.G. van Gelder,Sebastiaan L. Knijnenburg,A.C. van Arkel,Bert Meerman,Mark Wilkinson,Susanna-Assunta Sansone,Philippe Rocca-Serra,Peter McQuilton,Alejandra Gonzalez-Beltran,G.J.C. Aben,Patrícia Corrêa Henning,Maria Simone de Menezes Alencar,Claudio Jose Silva Ribeiro,Carlos Roberto Lyra da Silva,Luís Fernando Sayão,Luana Farias Sales,Viviane Santos de Oliveira Veiga,Jefferson Lima,Simone Faury Dib,Paula Xavier dos Santos,R. Murtinho,Jakob Tendel,Ben Schaap,P.M. Brouwer,Anand Gavai,Yamine Bouzembrak,Hans J.P. Marvin,Albert Mons,Tobias Kuhn,A.A. Gambardella,Ricardo de Miranda Azevedo,Vesa Muhonen,Mira van der Naald,N.W. Smit,M.J. Buys,Taco F. de Bruin,Fieke Schoots,H.J.E. Goodson,Henry Rzepa,Keith G. Jeffery,Hugh P. Shanahan,Myles Axton,Veniamin Tkachenko,Anne Deslattes Maya,Natalie Meyers,Michael Conlon,Laurel L. Haak,Erik Anthony Schultes +59 more
TL;DR: The outcome of a recent M4M workshop has led to a pilot programme involving two national science funders, the Health Research Board of Ireland and the Netherlands Organisation for Health Research and Development (ZonMW), which envisions a data-management workflow having seven essential stages, where solution providers are openly invited to participate.
Proceedings ArticleDOI
Workflow forever: semantic web semantic models and tools for preserving and digitally publishing computational experiments
Kristina Hettne,Stian Soiland-Reyes,Graham Klyne,Khalid Belhajjame,Matthew Gamble,Sean Bechhofer,Marco Roos,Oscar Corcho +7 more
TL;DR: It is argued that traditional journal publication is no longer sufficient, and a methodology based on the workflow paradigm, Semantic Web models, and Digital Library infrastructure is proposed, to enable the preservation of the necessary and sufficient information for researchers to understand the steps of a computational experiment that led to new biological insight, at any point in the future.