Kuangcai Chen

TL;DR: In this paper, the most recent achievements and challenges associated with using AuNPs to improve resolution and sensitivity in biological imaging in vitro and in vivo were discussed, including direct visualization of AuNs inside the biosystems using i) dark field (DF) microscopy, ii) differential interference contrast (DIC), and iii) other techniques, such as interferometric scattering microscopy and photothermal imaging.

TL;DR: The ability of targeting AuNRs to cancer cell surface integrins and the introduction of NIR light to generate a mild plasmonic photothermal effect caused broad regulation on cytoskeletal proteins, thus impairing cancer cell migration and providing a potential medical application for controlling cancer metastasis.

TL;DR: It is proposed that the AuNPs that are trapped at thenuclear membrane both add to the mechanical stiffness of the nucleus and stimulate the overexpression of lamin A/C located around the nuclear membrane, thus increasing nuclear stiffness and slowing cancer cell migration and invasion.

TL;DR: An overview of recent advances in super-resolution chemical imaging of surface reactions is provided, including chemical kinetics and reaction dynamics; active-site distributions on single-particle surfaces; and size-, shape-, and facet-dependent catalytic activities of individual nanocatalysts.

TL;DR: It is demonstrated that gold nanorods (AuNRs) and the introduction of near-infrared light could inhibit the cancer cell collective migration by altering the actin filaments and cell junctions with significantly triggered phosphorylation changes of essential proteins, using mass spectrometry-based phosphoproteomics.