L
L. Barth Reller
Researcher at Duke University
Publications - 6
Citations - 602
L. Barth Reller is an academic researcher from Duke University. The author has contributed to research in topics: Mycobacterium tuberculosis & corneal ulcer. The author has an hindex of 5, co-authored 6 publications receiving 519 citations. Previous affiliations of L. Barth Reller include NewYork–Presbyterian Hospital.
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Journal ArticleDOI
Better tests, better care: improved diagnostics for infectious diseases.
Angela M. Caliendo,David N. Gilbert,David N. Gilbert,Christine C. Ginocchio,Kimberly E. Hanson,Larissa S May,Thomas C. Quinn,Thomas C. Quinn,Fred C. Tenover,David Alland,Anne J. Blaschke,Robert A. Bonomo,Karen C. Carroll,Mary Jane Ferraro,Lisa R. Hirschhorn,W. Patrick Joseph,Tobi Karchmer,Ann T MacIntyre,L. Barth Reller,Audrey F. Jackson +19 more
TL;DR: The current diagnostic landscape, including unmet needs and emerging technologies, and the challenges to the development and clinical integration of improved tests are reviewed, and recommendations that address a host of identified barriers are presented.
Journal ArticleDOI
Bacteremic disseminated tuberculosis in sub-Saharan Africa: a prospective cohort study
John A. Crump,Habib O. Ramadhani,Anne B. Morrissey,Wilbrod Saganda,Mtumwa S. Mwako,Lan-Yan Yang,Lan-Yan Yang,Shein-Chung Chow,Boniface N. Njau,Godfrey S. Mushi,Venance P. Maro,L. Barth Reller,John Bartlett +12 more
TL;DR: In the era of free ART and access to tuberculosis treatment, almost one half of patients with M. tuberculosis bacteremia may die within a month of hospitalization, and advanced immunosuppression predicts death.
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Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the BacT/alert blood culture system.
Christopher D. Doern,Stanley Mirrett,Diane Halstead,Joan Abid,Pamela J. Okada,L. Barth Reller +5 more
TL;DR: PF Plus is an improved medium for detecting microorganisms that cause pediatric bloodstream infections and yielded more clinically significant microorganisms than the BacT/Alert blood culture system.
Journal ArticleDOI
Cefazolin as a class representative for oral cephalosporins and uncomplicated urinary tract infections caused by indicated Enterobacteriaceae.
Audrey N. Schuetz,William B. Brasso,Jared L. Crandon,Dwight J. Hardy,Stephen G. Jenkins,Ronald N. Jones,Cindy C. Knapp,L. Barth Reller +7 more
TL;DR: This study indicates that the addition of PZA in the treatment regimen of MDR-TB patients without susceptibility testing would have less benefit and might increase the risk of Extensively drugresistant tuberculosis (XDR- TB) development or render treatment ineffective.
Journal ArticleDOI
Performance of Nucleic Acid Amplification following Extraction of 5 Milliliters of Whole Blood for Diagnosis of Mycobacterium tuberculosis Bacteremia
John A. Crump,Marion J. Tuohy,Anne B. Morrissey,Habib O. Ramadhani,Boniface N. Njau,Venance P. Maro,L. Barth Reller,Gary W. Procop +7 more
TL;DR: The NAAT shows promise, but modifications should focus on improving sensitivity, and the test should be modified to reflect real-time PCR results.