L
L. Pinessi
Researcher at University of Florence
Publications - 1
Citations - 415
L. Pinessi is an academic researcher from University of Florence. The author has contributed to research in topics: Chromosome 21 & Genetic linkage. The author has an hindex of 1, co-authored 1 publications receiving 411 citations.
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Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder
P. St. George-Hyslop,Jonathan L. Haines,Lindsay A. Farrer,Ronald J. Polinsky,C. Van Broeckhoven,Alison Goate,D. R. Crapper McLachlan,Harry T. Orr,Amalia C. Bruni,Sandro Sorbi,Innocenzo Rainero,J. F. Foncin,Daniel A. Pollen,J. M. Cantu,Rossella Tupler,Rossella Tupler,Voskresenskaya Ni,Richard Mayeux,John H. Growdon,V. A. Fried,Richard H. Myers,Linda Nee,H Backhovens,J. J. Martin,Martin N. Rossor,M. J. Owen,Michael Mullan,M. E. Percy,H. Karlinsky,Stephen S. Rich,Leonard L. Heston,M.P. Montesi,M. Mortilla,N. Nacmias,James F. Gusella,John Hardy,K. Abe,Luigi Amaducci,L. Bergamini,Marc Bruyland,Stefano F. Cappa,Stefano F. Cappa,L. Connor,G. De Winter,David A. Drachman,Robert G. Feldman,M. Fracarro,M. Fracarro,M. E. Franco,P. Frommelt,Gavrilova Si,G. Gei,J. Gheuens,A. Haynes,J. Henry,L James,Marianne James,B. O'Donnell,Silvia Piacentini,L. Pinessi,P Roques,C. Ruiz,J. Swearer,Rudolph E. Tanzi,Antoon Vandenberghe,M. Vartanian,G. Vaula,Paul C. Watkins,Robert Williamson +68 more
TL;DR: The inheritance of five polymorphic DNA markers from the proximal long arm of chromosome 21 in a large unselected series of pedi-grees with familial Alzheimer's disease suggests that Alzheimer's Disease is not a single entity, but rather results from genetic defects on chromosome 21 and from other genetic or nongenetic factors.