L
Laura Magill
Researcher at University of Birmingham
Publications - 60
Citations - 2600
Laura Magill is an academic researcher from University of Birmingham. The author has contributed to research in topics: Medicine & Randomized controlled trial. The author has an hindex of 16, co-authored 45 publications receiving 1822 citations.
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Journal ArticleDOI
Value of Mismatch Repair, KRAS, and BRAF Mutations in Predicting Recurrence and Benefits From Chemotherapy in Colorectal Cancer
Gordon G A Hutchins,K Southward,Kelly Handley,Laura Magill,C Beaumont,Jens Stahlschmidt,Susan D. Richman,Philip A. Chambers,Matthew T. Seymour,David J. Kerr,Richard Gray,Philip Quirke +11 more
TL;DR: The usefulness of defective mismatch repair, BRAF, and KRAS mutations in predicting tumor recurrence and sensitivity to chemotherapy is investigated and MMR assays identify patients with a low risk of recurrence.
Journal ArticleDOI
Validation Study of a Quantitative Multigene Reverse Transcriptase–Polymerase Chain Reaction Assay for Assessment of Recurrence Risk in Patients With Stage II Colon Cancer
Richard Gray,Philip Quirke,Kelly Handley,Margarita Lopatin,Laura Magill,Frederick L. Baehner,C Beaumont,Kim M. Clark-Langone,Carl Yoshizawa,Mark Lee,Drew Watson,Steven Shak,David J. Kerr +12 more
TL;DR: The continuous 12-gene RS has been validated in a prospective study for assessment of recurrence risk in patients with stage II colon cancer after surgery and provides prognostic value that complements T stage and MMR.
Journal ArticleDOI
Global burden of postoperative death
Dmitri Nepogodiev,Janet Martin,Bruce M Biccard,Alex Makupe,Aneel Bhangu,Adesoji O Ademuyiwa,Adewale O. Adisa,Maria-Lorena Aguilera,Sohini Chakrabortee,J Edward Fitzgerald,Dhruv Ghosh,James Glasbey,Ewen M Harrison,J.C. Allen Ingabire,Hosni Salem,Marie Carmela M. Lapitan,Ismaïl Lawani,David Lissauer,Laura Magill,Rachel J. Moore,Daniel C. Osei-Bordom,Thomas Pinkney,Ahmad Uzair Qureshi,Antonio Ramos-De la Medina,Sarah Rayne,Sudha Sundar,Stephen Tabiri,Azmina Verjee,Raul Yepez,O. James Garden,Richard J. Lilford,Peter Brocklehurst,Dion Morton +32 more
Journal ArticleDOI
Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial)
Thomas Pinkney,Melanie Calvert,David C. Bartlett,Adrian Gheorghe,V Redman,George Dowswell,William G. Hawkins,Tony Mak,Haney Youssef,Caroline R. Richardson,Steven Hornby,Laura Magill,Richard Haslop,Sue Wilson,Dion Morton +14 more
TL;DR: Wound edge protection devices do not reduce the rate of surgical site infection in patients undergoing laparotomy, and therefore their routine use for this role cannot be recommended.
Journal ArticleDOI
Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial)
R. Ravikumar,David C. Bartlett,Dion Morton,L. Berkman,H. Bodenham-Chilton,Jonathan J Deeks,Kelly Handley,Laura Magill,E. Hamilton,Elizabeth Hepburn,M-J Hwang,Nazzia Mirza,A. Wilkey,M. le Breuilly L. Magill,A. Wilcockson,Samir Mehta,A. Burtenshaw,William G. Hawkins,M. Voysey,Jane M Blazeby,I. Smith,D. Stocken,S. Abbott,M. Hwang,A. Karim,D. P. Luke,D. McArthur,P. Mistry,J. Richardson,Haney Youssef,K. Ravi,P. B. Goodfellow,R. Gupta,H. Joy,N. Eardley,C. Mcfaul,D. Vimalachandran,C. Harmston,P. Froggatt,P. Krishnan,S. Pathare,V. Shanmugam,Y. J. Yiannakou,A. Fawole,C. Macklin,J. Mcenhill,Harjeet Narula,T. Riad,A. Rose,J. Chambers,C. Ekere,M. Hough,J. Hull,H. P. Knight,M. J. Lamparelli,Maxine A Lewis,M. Pulletz,N. Siddiqi,B. Stubbs,K. Subramanian,R. Swanton,S. Costigan,G. O'Connell,P. K. Patel,A. Ali,C. Ang,M. A. S. Chapman,U. Shariff,Christopher C. Thompson,A. Williamson J. Yates,D. J. Leinhardt,M. Simenacz,S. Harris,P. Loveless,Y. Mohsen,A. Myers,A. Prabhudesai,S. Vanagov,Kamal Aryal,R. Lal,D. Millican,I. Panagiotopopoulou,K. Shankar,Mukul Dube,J. Tansley,James Hill,S Addison,R. Church,J. Nath,S. Valap,A. Dhrampal,J. Nortje,J. Payne,K. Sargen,C. Speakman,J. Deloughry,T. Elkington,R. Dennis,S. Ghosh,Janet Martin,M. Stoker,N. Akerman,M. Basheer,N. Drury,C. Parchment-Smith,R. Sandhu,R. Srinivasa,S. Varma,S. Walwyn,N. Syed,J. Bromilow,P. Colling,H. Reschreiter,A. Senapati,F. Howse,L. Tzouliadis,S. Bach,A. Brookes,C. Cagigas,N. Dimitriou,S. Fallis,K. Futaba,A. Hill,A. Izbal,K. Leong,M. Manji,P. Milns,A. Murray,D. Nicol,Thomas Pinkney,S. Ramcharam,T. J. Royle,R. Scarpinata,C. Smart,S. Smart,Nigel Suggett,S. Sutherland,Y. H. M. Tam,A. Torrance,M. Wall,S. Vakis,M. Bassuini,J. Garner,S. Maz,M. Mottahedeh,Matthew E. Smith,M. Withers,R. Krishnamourthy,M. Paraoan,P. Thomas,N. Chesshire,S. Davies,S. Gold,I. Hamzah,N. Hurst,C. K. Khoo,S. Kiani,S. Liptrot,J. Lund,C. Millard,Christopher Morris,J. R. Reynolds,I. Selvaraj,A. Simpson,W. Speake,S. Tou,W. Chambers,A. S. Gee,A. Grice,D. Johnston,Q. Miller,J. Pittman,D. Price,R. Telford,E. Barrow,C. Coldwell,I. Crighton,T. Raymond,S. Richmond,M. Cheetham,G. Kulemeka,M. Carraretto,S. Huddart,J. Kirk-Bayley,D. Moor,M. Scott,M. Asif,R. Awan,R. Bethune,M. Chadwick,Tomas J. Cook,E. Courtney,S. Dalton,A. Lim,M. Williamson,James G. Wood,R. Scott,G. Branagan,J. Bellin,D. Browning,V. Bulso,N. Carter,N. Cruikshank,Kathryn Gill,N. Hulme,E. Leno,D. Newbould,V. Thumbe,K. Sankar,S. Sivasubramaniam,R. Wakhle,R. Walton,L. Zulueta,S. M. Ahmad,G. Kaur,D. Longbottom,M. Nnaji,A. Ramamoorthy,J. Thomas,I. Botteril,D. Miskovic,P. M. Sagar,S. Bhuptani,Robin H. Kennedy,I. Jenkins,S. Littler,G. Arnold,G. Buchanan,A. Con,P. Dawson,S. Lawrie,J. Lowe,S. Malhotra,P. Paraskeva,S. Richards,V. Sidhu,P. Ziprin,D. Kruchek,A. Kuttler,K. Mohammad,T. Nasser,H. Rehman,K.H. Siddiqui,A. Siddiqui,Q. Sindhu,M. Soliman,M.H. Solkar,S. Thota,Andrew G Renehan,Chelliah Selvasekar,H. Melsom,A. K. Agarwal,D. W. Borowski,F. Brohi,D. Garg,Talvinder Gill,V. Mahadevan,Abhiram Sharma,M. A. Tabaqchali,T. Alce,A. Navapurkar,V. Page,T. Stambach,P. Capozzi,Peter Coe,P. Conroy,S. Duff,T. Grey,O. Hill,J. Nicholson,D. Nolan,J. Pollard,A. Ramesh,M. Sabar,K. Telford,D. Davies,J. Wilson,D. Yates +277 more
TL;DR: Addition of a single dose of 8 mg intravenous dexamethasone at induction of anaesthesia significantly reduces both the incidence of postoperative nausea and vomiting at 24 hours and the need for rescue antiemetics for up to 72 hours in patients undergoing large and small bowel surgery, with no increase in adverse events.