L
L. Berkman
Researcher at National Council of Resistance of Iran
Publications - 6
Citations - 310
L. Berkman is an academic researcher from National Council of Resistance of Iran. The author has contributed to research in topics: Randomized controlled trial & Clinical trial. The author has an hindex of 5, co-authored 6 publications receiving 235 citations.
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Journal ArticleDOI
ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours.
C. Coyle,Fay H. Cafferty,S Rowley,Mairead MacKenzie,L. Berkman,Sudeep Gupta,C.S. Pramesh,Duncan C. Gilbert,Howard Kynaston,David Cameron,Richard H. Wilson,Alistair Ring,Ruth E Langley +12 more
TL;DR: The Add-Aspirin trial investigates whether regular aspirin use after standard therapy prevents recurrence and prolongs survival in participants with four non-metastatic common solid tumours.
Journal ArticleDOI
Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial)
R. Ravikumar,David C. Bartlett,Dion Morton,L. Berkman,H. Bodenham-Chilton,Jonathan J Deeks,Kelly Handley,Laura Magill,E. Hamilton,Elizabeth Hepburn,M-J Hwang,Nazzia Mirza,A. Wilkey,M. le Breuilly L. Magill,A. Wilcockson,Samir Mehta,A. Burtenshaw,William G. Hawkins,M. Voysey,Jane M Blazeby,I. Smith,D. Stocken,S. Abbott,M. Hwang,A. Karim,D. P. Luke,D. McArthur,P. Mistry,J. Richardson,Haney Youssef,K. Ravi,P. B. Goodfellow,R. Gupta,H. Joy,N. Eardley,C. Mcfaul,D. Vimalachandran,C. Harmston,P. Froggatt,P. Krishnan,S. Pathare,V. Shanmugam,Y. J. Yiannakou,A. Fawole,C. Macklin,J. Mcenhill,Harjeet Narula,T. Riad,A. Rose,J. Chambers,C. Ekere,M. Hough,J. Hull,H. P. Knight,M. J. Lamparelli,Maxine A Lewis,M. Pulletz,N. Siddiqi,B. Stubbs,K. Subramanian,R. Swanton,S. Costigan,G. O'Connell,P. K. Patel,A. Ali,C. Ang,M. A. S. Chapman,U. Shariff,Christopher C. Thompson,A. Williamson J. Yates,D. J. Leinhardt,M. Simenacz,S. Harris,P. Loveless,Y. Mohsen,A. Myers,A. Prabhudesai,S. Vanagov,Kamal Aryal,R. Lal,D. Millican,I. Panagiotopopoulou,K. Shankar,Mukul Dube,J. Tansley,James Hill,S Addison,R. Church,J. Nath,S. Valap,A. Dhrampal,J. Nortje,J. Payne,K. Sargen,C. Speakman,J. Deloughry,T. Elkington,R. Dennis,S. Ghosh,Janet Martin,M. Stoker,N. Akerman,M. Basheer,N. Drury,C. Parchment-Smith,R. Sandhu,R. Srinivasa,S. Varma,S. Walwyn,N. Syed,J. Bromilow,P. Colling,H. Reschreiter,A. Senapati,F. Howse,L. Tzouliadis,S. Bach,A. Brookes,C. Cagigas,N. Dimitriou,S. Fallis,K. Futaba,A. Hill,A. Izbal,K. Leong,M. Manji,P. Milns,A. Murray,D. Nicol,Thomas Pinkney,S. Ramcharam,T. J. Royle,R. Scarpinata,C. Smart,S. Smart,Nigel Suggett,S. Sutherland,Y. H. M. Tam,A. Torrance,M. Wall,S. Vakis,M. Bassuini,J. Garner,S. Maz,M. Mottahedeh,Matthew E. Smith,M. Withers,R. Krishnamourthy,M. Paraoan,P. Thomas,N. Chesshire,S. Davies,S. Gold,I. Hamzah,N. Hurst,C. K. Khoo,S. Kiani,S. Liptrot,J. Lund,C. Millard,Christopher Morris,J. R. Reynolds,I. Selvaraj,A. Simpson,W. Speake,S. Tou,W. Chambers,A. S. Gee,A. Grice,D. Johnston,Q. Miller,J. Pittman,D. Price,R. Telford,E. Barrow,C. Coldwell,I. Crighton,T. Raymond,S. Richmond,M. Cheetham,G. Kulemeka,M. Carraretto,S. Huddart,J. Kirk-Bayley,D. Moor,M. Scott,M. Asif,R. Awan,R. Bethune,M. Chadwick,Tomas J. Cook,E. Courtney,S. Dalton,A. Lim,M. Williamson,James G. Wood,R. Scott,G. Branagan,J. Bellin,D. Browning,V. Bulso,N. Carter,N. Cruikshank,Kathryn Gill,N. Hulme,E. Leno,D. Newbould,V. Thumbe,K. Sankar,S. Sivasubramaniam,R. Wakhle,R. Walton,L. Zulueta,S. M. Ahmad,G. Kaur,D. Longbottom,M. Nnaji,A. Ramamoorthy,J. Thomas,I. Botteril,D. Miskovic,P. M. Sagar,S. Bhuptani,Robin H. Kennedy,I. Jenkins,S. Littler,G. Arnold,G. Buchanan,A. Con,P. Dawson,S. Lawrie,J. Lowe,S. Malhotra,P. Paraskeva,S. Richards,V. Sidhu,P. Ziprin,D. Kruchek,A. Kuttler,K. Mohammad,T. Nasser,H. Rehman,K.H. Siddiqui,A. Siddiqui,Q. Sindhu,M. Soliman,M.H. Solkar,S. Thota,Andrew G Renehan,Chelliah Selvasekar,H. Melsom,A. K. Agarwal,D. W. Borowski,F. Brohi,D. Garg,Talvinder Gill,V. Mahadevan,Abhiram Sharma,M. A. Tabaqchali,T. Alce,A. Navapurkar,V. Page,T. Stambach,P. Capozzi,Peter Coe,P. Conroy,S. Duff,T. Grey,O. Hill,J. Nicholson,D. Nolan,J. Pollard,A. Ramesh,M. Sabar,K. Telford,D. Davies,J. Wilson,D. Yates +277 more
TL;DR: Addition of a single dose of 8 mg intravenous dexamethasone at induction of anaesthesia significantly reduces both the incidence of postoperative nausea and vomiting at 24 hours and the need for rescue antiemetics for up to 72 hours in patients undergoing large and small bowel surgery, with no increase in adverse events.
Journal ArticleDOI
The Development of an Umbrella Trial (PLATO) to Address Radiation Therapy Dose Questions in the Locoregional Management of Squamous Cell Carcinoma of the Anus
David Sebag-Montefiore,Richard Adams,Sandra M. Bell,L. Berkman,Duncan C. Gilbert,Rob Glynne-Jones,Vicky Goh,Walter M Gregory,Mark Harrison,Lisa A. Kachnic,Mark T Lee,Lucy McParland,Rebecca Muirhead,B.D. O'Neill,G.G. Hutchins,Sheela Rao,Andrew G Renehan,Alison Smith,Galina Velikova,Maria A. Hawkins +19 more
TL;DR: The PLATO (personalizing radiotherapy dose in anal cancer) umbrella trial comprising of the ACT3, 4 and 5 trials is funded by Cancer Research UK and is due to commence recruitment in Q3 2016 as discussed by the authors.
Journal ArticleDOI
Aspirin as an adjuvant treatment for cancer: feasibility results from the Add-Aspirin randomised trial.
Nalinie Joharatnam-Hogan,Fay H. Cafferty,Richard A Hubner,Daniel Swinson,Sharmila Sothi,Kamalnayan Gupta,Stephen Falk,Kinnari Patel,Nicola Warner,Victoria Kunene,Sam Rowley,Komel Khabra,Timothy J. Underwood,Janusz Jankowski,John Bridgewater,Anne Crossley,Verity Henson,L. Berkman,Duncan C. Gilbert,Howard Kynaston,Alistair Ring,David Cameron,Farhat V N Din,Janet Graham,Timothy Iveson,Richard Adams,Anne L. Thomas,Richard H. Wilson,C.S. Pramesh,Ruth E. Langley,John Burn,Sue Campbell,Lisa Capaldi,Yvonne Carse,Durga Gadgil,Arnold Goldman,Sudeep Gupta,Gregory Leonard,Mairead MacKenzie,Mahesh K. B. Parmar,Carlo Patrono,Russell D. Petty,Peter M. Rothwell,Robert Steele +43 more
TL;DR: Toxicity has been low and there is no evidence of a difference in adherence, acceptance of randomisation, or toxicity between the different cancer cohorts, and trial recruitment continues to determine whether aspirin could offer a potential low cost and well tolerated therapy to improve cancer outcomes.
Journal ArticleDOI
Co-enrolment of Participants into Multiple Cancer Trials: Benefits and Challenges
TL;DR: The benefits and challenges associated with co-enrolment are discussed based on experiences in the Add-Aspirin trial – a large, multicentre trial recruiting across a number of tumour types, where opportunities to co- enrol patients have been proactively explored and managed.