L
Lea Steele
Researcher at Baylor College of Medicine
Publications - 11
Citations - 598
Lea Steele is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Environmental exposure & Medicine. The author has an hindex of 5, co-authored 11 publications receiving 478 citations. Previous affiliations of Lea Steele include Baylor University.
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Journal ArticleDOI
Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment
Roberta F. White,Lea Steele,James P. O'Callaghan,Kimberly Sullivan,James H. Binns,Beatrice A. Golomb,Floyd E. Bloom,James A. Bunker,Fiona Crawford,Joel C. Graves,Anthony Hardie,Nancy G. Klimas,Marguerite L. Knox,William J. Meggs,Jack Melling,Martin A. Philbert,Rachel Grashow +16 more
TL;DR: It is concluded that exposure to pesticides and/or to PB are causally associated with GWI and the neurological dysfunction in GW veterans and Gene-environment interactions are likely to have contributed to development of GWI in deployed veterans.
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Complex Factors in the Etiology of Gulf War Illness: Wartime Exposures and Risk Factors in Veteran Subgroups
TL;DR: Findings support a role for a limited number of wartime exposures in the etiology of GWI, which differed in importance with the deployment milieu in which veterans served.
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Butyrylcholinesterase genotype and enzyme activity in relation to Gulf War illness: preliminary evidence of gene-exposure interaction from a case–control study of 1991 Gulf War veterans
TL;DR: Preliminary evidence is provided that military personnel with certain BChE genotypes who used PB during the 1991 Gulf War may have been at particularly high risk for developing GWI.
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The Multiple Hit Hypothesis for Gulf War Illness: Self-Reported Chemical/Biological Weapons Exposure and Mild Traumatic Brain Injury.
Patricia A. Janulewicz,Maxine Krengel,Emily Quinn,Timothy Heeren,Rosemary Toomey,Ronald J. Killiany,Clara G. Zundel,Joy Ajama,James P. O'Callaghan,Lea Steele,Nancy G. Klimas,Kimberly Sullivan +11 more
TL;DR: Both exposure to mTBI and CBW are associated with the development of GWI and multiple chronic health conditions and that combined exposure appears to lead to higher risk of chronic health effects.
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Alterations in high-order diffusion imaging in veterans with Gulf War Illness is associated with chemical weapons exposure and mild traumatic brain injury.
Chia-Hsin Cheng,Bang-Bon Koo,Samantha M. Calderazzo,Emily Quinn,Kristina K. Aenlle,Lea Steele,Nancy G. Klimas,Maxine Krengel,Patricia A. Janulewicz,Rosemary Toomey,Lindsay T. Michalovicz,Kimberly A. Kelly,Timothy Heeren,Deborah Little,James P. O'Callaghan,Kimberly Sullivan +15 more
TL;DR: These results suggest TNF signaling mediated inflammation affects frontal and limbic regions of the brain, which may contribute to the fatigue and sleep symptoms of the disease and suggest a strong neuroinflammatory component to GWI.