L
Lenka Hernychová
Researcher at University of Defence
Publications - 75
Citations - 1480
Lenka Hernychová is an academic researcher from University of Defence. The author has contributed to research in topics: Francisella tularensis & Proteome. The author has an hindex of 22, co-authored 62 publications receiving 1319 citations. Previous affiliations of Lenka Hernychová include Military Medical Academy.
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Journal ArticleDOI
The immunomodulatory effect(s) of lead and cadmium on the cells of immune system in vitro.
TL;DR: The results suggest the metal-induced changes in immunoregulatory mechanism of host with potentially severe clinical consequences.
Journal ArticleDOI
Mapping of immunoreactive antigens of Francisella tularensis live vaccine strain
Jana Havlasová,Lenka Hernychová,Petr Halada,Vera Pellantova,Jan Krejsek,Jiri Stulik,Aleš Macela,Peter R. Jungblut,Pär Larsson,Mats Forsman +9 more
TL;DR: Comprehensive mapping of immunoreactive antigens using the attenuated live vaccine strain of F. tularensis LVS originating from the European virulent strain finds that 60 kDa and 10 kDa chaperonins that occurred in several charge and mass variants, predominated.
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Proteomic analysis of anti-Francisella tularensis LVS antibody response in murine model of tularemia.
Jana Havlasová,Lenka Hernychová,Martin Brychta,Martin Hubálek,Jurai Lenco,Pär Larsson,Pär Larsson,Margaretha Lundqvist,Mats Forsman,Zulana Kročová,Jiri Stulik,Aks Macela +11 more
TL;DR: The antibody patterns of the two strains showed significant homogeneity in being directed against almost identical subset of antigens, and the spectrum of immunoreactive spots detected by two‐dimensional immunoblotting varied throughout the course of infection depending on murine strain.
Journal ArticleDOI
Proteome study of colorectal carcinogenesis.
Jiri Stulik,Lenka Hernychová,Stanislava Porkertová,Jiri Knizek,Aleš Macela,Bures J,Jandík P,Jim I. Langridge,Peter R. Jungblut +8 more
TL;DR: The alterations in the expression of nine proteins were common for both precancerous and neoplastic tissues suggesting their role in colon tumorigenesis, and 18 were annotated by mass spectrometry.
Journal ArticleDOI
Proteomic analysis of wheat proteins recognized by IgE antibodies of allergic patients.
Petr Šotkovský,Martin Hubálek,Lenka Hernychová,Petr Novák,Marie Havranova,Iva Šetinová,Andrea Kitanovičová,Martin Fuchs,Jiří Stulík,Ludmila Tučková +9 more
TL;DR: These findings contribute to the identification of wheat allergens aimed to increase the specificity of serum IgE and cell activation diagnostic assays.