L
Lennart Opitz
Researcher at University of Zurich
Publications - 92
Citations - 4487
Lennart Opitz is an academic researcher from University of Zurich. The author has contributed to research in topics: Transcriptome & Stem cell. The author has an hindex of 31, co-authored 84 publications receiving 3490 citations. Previous affiliations of Lennart Opitz include University of Göttingen & École Polytechnique Fédérale de Lausanne.
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Journal ArticleDOI
X-Linked Lymphoproliferative Disease Mimicking Multisystem Inflammatory Syndrome in Children-A Case Report
Seraina Prader,Nicole Ritz,Nicole Ritz,Frederic Baleydier,Maya C. André,Noémie Stähli,Kevin Schmid,Hanna Schmid,Andreas Woerner,Tamara Diesch,Patrick M. Meyer Sauteur,Johannes Trück,Fabienne Gebistorf,Lennart Opitz,Michael P. Killian,Tommaso Marchetti,Stefano Vavassori,Geraldine Blanchard-Rohner,Valerie Mc Lin,Serge Grazioli,Jana Pachlopnik Schmid,Jana Pachlopnik Schmid +21 more
TL;DR: In this paper, a male patient fulfilling the diagnostic criteria of MIS-C, who was initially treated according to current consensus guidelines, was diagnosed with X-linked lymphoproliferative disease type 1 (XLP1).
Journal ArticleDOI
Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes.
Ursina Nüesch,Andrea A. Mauracher,Lennart Opitz,Lennart Opitz,Benjamin Volkmer,Katarzyna Michalak-Micka,Jivko Kamarashev,Tom Hartwig,Ernst Reichmann,Burkhard Becher,Stefano Vavassori,Jana Pachlopnik Schmid,Jana Pachlopnik Schmid +12 more
TL;DR: The results reveal a previously unsuspected fundamental cell‐extrinsic role of Ttc7, and identify potential candidates for molecularly targeted treatment strategies that will need to be evaluated in future preclinical studies.
Journal ArticleDOI
Defining the molecular landscape of cancer-associated stroma in cutaneous squamous cell carcinoma.
Erin Beebe,Zahra Motamed,Lennart Opitz,Phil F. Cheng,Mitchell P. Levesque,Enni Emilia Markkanen,Laurence Feldmeyer +6 more
TL;DR: In this paper , the authors analyzed cancer-associated stroma (CAS) and matched normal stroma from 20 cSCC cases (11 without PNI and 9 with PNI) using RNA sequencing.
Posted ContentDOI
Engineered Peptide Barcodes for In-Depth Analyses of Binding Protein Ensembles
Pascal Egloff,Iwan Zimmermann,Fabian M. Arnold,Cedric A. J. Hutter,Damien Morger,Lennart Opitz,Lucy Poveda,Hans-Anton Keserue,Christian Panse,Bernd Roschitzki,Markus A. Seeger +10 more
TL;DR: NestLink, a binder selection and identification technology able to biophysically characterize thousands of library members at once without handling individual clones at any stage of the process, was developed and applied to overcome current limitations of binder generation.