L
Lennart Opitz
Researcher at University of Zurich
Publications - 92
Citations - 4487
Lennart Opitz is an academic researcher from University of Zurich. The author has contributed to research in topics: Transcriptome & Stem cell. The author has an hindex of 31, co-authored 84 publications receiving 3490 citations. Previous affiliations of Lennart Opitz include University of Göttingen & École Polytechnique Fédérale de Lausanne.
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Unusual dermatological presentation and immune phenotype in SCID due to an IL7R mutation: the value of whole-exome sequencing and the potential benefit of newborn screening
L. Marquardt,M. Lacour,M. Hoernes,Lennart Opitz,Lennart Opitz,R. Lecca,Benjamin Volkmer,Janine Reichenbach,Daniel Hohl,Marc Ansari,Hulya Ozsahin,Tayfun Güngör,J Pachlopnik Schmid +12 more
TL;DR: A 2-month-old girl who presented with erythroderma and axillary lymphadenopathies, followed by the development of hepatosplenomegaly with leucocytosis, lymphocyTosis and eosinophilia over the next few months, was diagnosed with severe combined immunodeficiency and died at the age of 34 months.
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Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Wenfei Sun,Hua Dong,Anton S. Becker,Anton S. Becker,Dianne H. Dapito,Salvatore Modica,Gerald Grandl,Lennart Opitz,Lennart Opitz,Vissarion Efthymiou,Leon G. Straub,Gitalee Sarker,Miroslav Balaz,Lucia Balazova,Aliki Perdikari,Elke Kiehlmann,Sara Bacanovic,Caroline Zellweger,Daria Peleg-Raibstein,Pawel Pelczar,Wolf Reik,Wolf Reik,Irene A. Burger,Ferdinand von Meyenn,Ferdinand von Meyenn,Christian Wolfrum +25 more
TL;DR: In the version of this article originally published, the months on the axis labeled projected month of conception in Fig. 1a were out of order.
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Large-Scale Integrative Analysis of Epigenetic Modifications Induced by Isotretinoin, Doxycycline and Metronidazole in Murine Colonic Intestinal Epithelial Cells
Eugenia Becker,Susan Bengs,Sirisha Aluri,Lennart Opitz,Kirstin Atrott,Felix Rost,Irina Leonardi,Claudia Stanzel,Tina Raselli,Stephanie Kasper,Pedro A. Ruiz,Gerhard Rogler +11 more
TL;DR: Whether doxycycline, metronidazole, or isotretinoin are able to induce alterations in DNA methylation and microRNA expression patterns in murine colonic intestinal epithelial cells (IECs) is studied and novel microRNAs were identified, which might be of relevance in IEC development.
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Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice
Sereina Deplazes,Andrea Schlegel,Zhuolun Song,Gabriella Allegri,Nicole Rimann,Tanja Scherer,Melanie Willimann,Lennart Opitz,Sharon C. Cunningham,Ian E. Alexander,Anja Kipar,Johannes Häberle,Beat Thöny,Hiu Man Grisch-Chan +13 more
TL;DR: In this article , a minicircle vector was used to correct periportal hepatic defects such as phenylketonuria and cystathionine β-synthase deficiency.
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Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
TL;DR: In this paper , the authors analyzed cancer-associated stroma (CAS) and matched normal stroma from 16 non-metastatic and 15 metastatic CMTs by RNA-sequencing of micro-dissected FFPE tissue.