L
Leonid Poretsky
Researcher at Lenox Hill Hospital
Publications - 22
Citations - 1333
Leonid Poretsky is an academic researcher from Lenox Hill Hospital. The author has contributed to research in topics: Insulin & Insulin-like growth factor. The author has an hindex of 11, co-authored 22 publications receiving 1116 citations. Previous affiliations of Leonid Poretsky include NewYork–Presbyterian Hospital & University of South Carolina.
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Journal ArticleDOI
The insulin-related ovarian regulatory system in health and disease.
TL;DR: The Insulin-Related Ovarian Regulatory System: Implications for Therapy and Therapeutic use are summarized.
Journal ArticleDOI
The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review.
TL;DR: Assessment of circulating and tissue AGE levels in identifying asymptomatic patients at risk for CAD or to identify patients who may benefit from invasive intervention suggests AGEs and their receptors may be useful biomarkers for the presence and severity of CAD.
Journal ArticleDOI
Phosphatidyl-inositol-3 kinase-independent insulin action pathway(s) in the human ovary.
Leonid Poretsky,Leonid Poretsky,Donna Seto-Young,Anil Shrestha,Sandeep Dhillon,Mana Mirjany,Hung-Ching Liu,Melissa C. Yih,Zev Rosenwaks +8 more
TL;DR: It is reported that activation of phosphatidyl-inositol-3 (PI-3) kinase, which is crucial for glucose transport, is not necessary for the insulin-induced stimulation of progesterone production or for the diabetes-induced inhibition of insulin-like growth factor binding protein 1 (IGFBP-1) production in cultured human ovarian cells.
Journal ArticleDOI
Phyto-polyphenols as potential inhibitors of breast cancer metastasis.
Dimiter Avtanski,Leonid Poretsky +1 more
TL;DR: Some phyto- polyphenols show low level of toxicity to untransformed cells, but selective suppressing effects on cancer cells proliferation and differentiation, in vitro and in vivo.
Journal ArticleDOI
Resistin induces breast cancer cells epithelial to mesenchymal transition (EMT) and stemness through both adenylyl cyclase-associated protein 1 (CAP1)-dependent and CAP1-independent mechanisms
Dimiter Avtanski,Dimiter Avtanski,Dimiter Avtanski,Anabel Garcia,Beatriz Caraballo,Priyanthan Thangeswaran,Sela Marin,Julianna Bianco,Aaron Lavi,Leonid Poretsky +9 more
TL;DR: The results demonstrate that resistin promotes the metastatic potential of breast cancer cells by inducing EMT and stemness and some of these effects are mediated by CAP1.