Liang Gu

TL;DR: It is found that donor cell chromatin transforms to the metaphase state rapidly after SCNT along with the dissolution of typical 3D chromatin structure, and insight is provided into chromatin architecture reorganisation during SCNT embryo development.

TL;DR: Estimation in the confidence of the tree selection strongly supported the phylogenetic affiliation of tree shrews to Primates as a monophyly and identified 6845 orthologous genes between seventeen placental mammals.

TL;DR: Comparison of the gene expression profiles of HEK293T cells with BDE-209 treatment and the negative control found that BDE -209 exposure may alter nucleosome organization through significantly changing the expression of histone gene clusters, indicating carcinogenic potential for a variety of tumors.

TL;DR: Wang et al. as discussed by the authors constructed a mouse AMI model and profiled transcriptomes and proteomes at the early stages of AMI progress, and found that WIPI1 was significantly upregulated at 1 h after AMI.

TL;DR: In this article, the authors identify six new ApiAP2 members associated with gametocytogenesis in Plasmodium falciparum, including PfAP2-G5 (PF3D7_1139300), which suppresses the transcriptional activity of the pfap2-g gene via binding to both the upstream region and exonic gene body, thereby preventing initiation of sexual commitment.