Liang Ma

TL;DR: It is demonstrated that Indigenous spore-forming bacteria from the mouse and human microbiota promote 5-HT biosynthesis from colonic enterochromaffin cells (ECs), which supply 5- HT to the mucosa, lumen, and circulating platelets and elevating luminal concentrations of particular microbial metabolites increases colonic and blood5-HT in germ-free mice.

TL;DR: Isolate microfluidicus 1 is, to the authors' knowledge, the first successful example of targeted cultivation of a microorganism from the high-priority group of the Human Microbiome Project’s “Most Wanted” list, and the first cultured representative of a previously unidentified genus of the Ruminococcaceae family.

TL;DR: The design, fabrication, biological validation, and underlying physics of a microfluidic SlipChip device that addresses the challenge of isolation of a novel microbial taxon and provides a facile way to cultivate anaerobes from complex communities.

TL;DR: A multistep SlipChip microfluidic device is presented for generatingserial dilution nanoliter arrays in high throughput with a series of simple sliding motions and an eight-step serial dilution SlipChip with a dilution ratio of 1:4 is applied for digital loop-mediated isothermal amplification across a large dynamic range and tested for hepatitis B viral load quantification with clinical samples.

TL;DR: This review aims to provide an overview of droplet microfluidics techniques for microbial research, from high-throughput single-cell cultivation, screening to the targeted or whole-genome sequencing of single cells.