Liangliang Zhang

TL;DR: The high consistence between the proposed approach RCA-assisted CRISPR/Cas9 cleavage (RACE) and reverse transcription quantitative polymerase chain reaction (RT-qPCR) in detecting EV-derived miRNAs abundance from both cultured cancer cells and clinical lung cancer patients validated its robustness, revealing its potentials in the screening, diagnosis and prognosis of various diseases.

TL;DR: A near-infrared light (NIR)-activated nanoprobe for high-sensitive in situ controllable miRNA imaging in living cells is proposed and remarkedly increases imaging efficiency by eliminating those unfavored intercellular molecular imaging background.

TL;DR: A fLuorescent Intracellular-Guided Hairpin-Tetrahedron (fLIGHT) nanoprobe is described, which enables high-fidelity fluorescence visualization of sEVs' microRNA without RNA extraction or leakage, demonstrating the potential of on-site tracing of s EV cargoes.

TL;DR: In this paper, a flipping identification with a prompt error-discrimination (FLIPPED) platform for automatic blood group readouts is presented, where green dye was exploited as a characteristic chromatography indicator for the differentiation of plasma from whole blood by presenting a teal color against a brown color.