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Xiaohui Chen
Researcher at Chongqing University
Publications - 16
Citations - 249
Xiaohui Chen is an academic researcher from Chongqing University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 5 publications receiving 82 citations. Previous affiliations of Xiaohui Chen include Third Military Medical University.
Papers
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Journal ArticleDOI
Rolling Circular Amplification (RCA)-Assisted CRISPR/Cas9 Cleavage (RACE) for Highly Specific Detection of Multiple Extracellular Vesicle MicroRNAs
Ruixuan Wang,Ruixuan Wang,Ruixuan Wang,Xianxian Zhao,Xiaohui Chen,Xiaopei Qiu,Xiaopei Qiu,Guangchao Qing,Hong Zhang,Liangliang Zhang,Xiaolin Hu,Zhuoqi He,Daidi Zhong,Ying Wang,Yang Luo +14 more
TL;DR: The high consistence between the proposed approach RCA-assisted CRISPR/Cas9 cleavage (RACE) and reverse transcription quantitative polymerase chain reaction (RT-qPCR) in detecting EV-derived miRNAs abundance from both cultured cancer cells and clinical lung cancer patients validated its robustness, revealing its potentials in the screening, diagnosis and prognosis of various diseases.
Journal ArticleDOI
Natural and engineered bacterial outer membrane vesicles
Guangchao Qing,Guangchao Qing,Guangchao Qing,Ningqiang Gong,Xiaohui Chen,Jing Chen,Hong Zhang,Yongchao Wang,Ruifang Wang,Shouwen Zhang,Zhen Zhang,Xianxian Zhao,Yang Luo,Yang Luo,Xing-Jie Liang +14 more
TL;DR: In this review, several methods including ultracentrifugation and precipitation for isolating OMVs were summarized and the importance of genetic engineering for the safe and effective application and in facilitating the rapid development of OMVs was highlighted.
Journal ArticleDOI
High‐Fidelity Determination and Tracing of Small Extracellular Vesicle Cargoes
Xiaohui Chen,Mei Jia,Lianhua Liu,Xiaopei Qiu,Xiaopei Qiu,Hong Zhang,Xingle Yu,Wei Gu,Guangchao Qing,Qingmei Li,Xiaolin Hu,Ruixuan Wang,Xianxian Zhao,Liangliang Zhang,Xianfeng Wang,Colm Durkan,Nan Wang,Guixue Wang,Yang Luo +18 more
TL;DR: A fLuorescent Intracellular-Guided Hairpin-Tetrahedron (fLIGHT) nanoprobe is described, which enables high-fidelity fluorescence visualization of sEVs' microRNA without RNA extraction or leakage, demonstrating the potential of on-site tracing of s EV cargoes.
Journal ArticleDOI
Carbon Nanomaze for Biomolecular Detection with Zeptomolar Sensitivity
Jing Bao,Jing Bao,Xiaopei Qiu,Deqiang Wang,Huisi Yang,Jiaying Zhao,Yanli Qi,Liangliang Zhang,Xiaohui Chen,Mei Yang,Wei Gu,Danqun Huo,Yang Luo,Changjun Hou +13 more
Journal ArticleDOI
Flipped Quick-Response Code Enables Reliable Blood Grouping.
Hong Zhang,Ruining Liu,Qingmei Li,Xiaolin Hu,Lixiang Wu,Ye Zhou,Guangchao Qing,Rui Yuan,Junjie Huang,Wei Gu,Yanyao Ye,Chao Qi,Mei Han,Xiaohui Chen,Xun Zhu,Yun Deng,Liangliang Zhang,Hengyi Chen,Haoran Zhang,Weiyin Gao,Yao Liu,Yang Luo +21 more
TL;DR: In this paper, a flipping identification with a prompt error-discrimination (FLIPPED) platform for automatic blood group readouts is presented, where green dye was exploited as a characteristic chromatography indicator for the differentiation of plasma from whole blood by presenting a teal color against a brown color.