L
Lichen Yin
Researcher at Soochow University (Suzhou)
Publications - 155
Citations - 9942
Lichen Yin is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Gene delivery & Chemistry. The author has an hindex of 46, co-authored 126 publications receiving 7825 citations. Previous affiliations of Lichen Yin include Fudan University & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles.
TL;DR: In vivo biodistribution suggested that NPs with slight negative charges and particle size of 150 nm were tended to accumulate in tumor more efficiently, and could serve as a guideline in the rational design of drug nanocarriers with maximized therapeutic efficacy and predictable in vivo properties.
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Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery.
TL;DR: Self-assembled nanoparticles between TMC-Cys and protein drugs could be an effective and safe oral delivery system and biocompatibility assessment revealed lack of toxicity of TMC -Cys NP.
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Superporous hydrogels containing poly(acrylic acid-co-acrylamide)/O-carboxymethyl chitosan interpenetrating polymer networks.
TL;DR: Due to the cross-linked O-CMC network, in vitro muco-adhesive force and mechanical properties, including compression and tensile modulus, of the SPH-IPN were greatly improved when compared with the CSPH.
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Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications
Hua Lu,Jing Wang,Ziyuan Song,Lichen Yin,Yanfeng Zhang,Haoyu Tang,Chunlai Tu,Yao Lin,Jianjun Cheng +8 more
TL;DR: Recent advances in amino acid N-carboxyanhydrides (NCAs) and synthetic polypeptides from the aspects of chemistry, self-assembly and biological applications are highlighted.
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Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application
Ziyuan Song,Zhiyuan Han,Shixian Lv,Shixian Lv,Chongyi Chen,Chongyi Chen,Li Chen,Li Chen,Lichen Yin,Jianjun Cheng +9 more
TL;DR: This review article highlights the recent advances in the design of polypeptide-based supramolecular structures, including complexes with nucleic acids, micelles, vesicles, hybrid nanoparticles, and hydrogels, and discusses the future opportunities in this field.