Lijun Shang

TL;DR: In this paper, the authors summarized the animal models used in the research of nanoparticles for CVD and provided a generic picture of current use of CVD animal models according to the different types of diseases.

TL;DR: The gating kinetics of different mutations within key parts of this extensive gating network suggest that the structure of the transition state (TS), which connects the pre-open and closed states of the channel, more closely resembles the structureOf thePre-open state.

TL;DR: The Tianjin Biosecurity Guidelines for Codes of Conduct for Scientists (TBCG) as mentioned in this paper have been developed over the last two decades to assist in the implementation of the guidelines, and a small-scale survey was carried out in early 2022 to discover what resources and experience have been accumulated, and it was argued that much of what is needed to implement the guidelines effectively has been developed, but that there are specific deficiencies that need to be remedied quickly.

TL;DR: It is found that GLP-2 inhibited food intake in fasted rats after a short-term intervention in a dose-dependent manner and this effect could be blocked functionally by Exendin(9-39).

TL;DR: This study examines the electrophysiological properties of other mutations identified in the human KCNK18 gene and finds that several of these variants also produce a dramatic dominant-negative phenotype and further supports the role of this channel as a potential therapeutic target.