L
Lilli T. E. Bay
Researcher at Oslo University Hospital
Publications - 6
Citations - 55
Lilli T. E. Bay is an academic researcher from Oslo University Hospital. The author has contributed to research in topics: RNA polymerase II & Medicine. The author has an hindex of 2, co-authored 4 publications receiving 9 citations.
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Journal ArticleDOI
WDR82/PNUTS-PP1 prevents transcription-replication conflicts by promoting RNA POLYMERASE II degradation on chromatin
Helga B. Landsverk,Lise E. Sandquist,Lilli T. E. Bay,Barbara Steurer,Coen Campsteijn,Ole J. B. Landsverk,Jurgen A. Marteijn,Eva Petermann,Laura Trinkle-Mulcahy,Randi G. Syljuåsen +9 more
TL;DR: It is suggested thatRNAPII-CTD dephosphorylation is required for the continuous turnover of RNAPII on chromatin, thereby preventing T-R conflicts.
Journal ArticleDOI
Expanding roles of cell cycle checkpoint inhibitors in radiation oncology.
Sissel Hauge,Adrian Eek Mariampillai,Gro Elise Rødland,Lilli T. E. Bay,Helga B. Landsverk,Randi G. Syljuåsen +5 more
TL;DR: The WEE1, CHK1, and ATR kinases are key factors in cell cycle checkpoint regulation and are essential for checkpoint regulation as discussed by the authors, however, they are not essential for activation.
Journal ArticleDOI
Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells.
Gro Elise Rødland,Sissel Hauge,Grete Hasvold,Lilli T. E. Bay,Tine T. H. Raabe,Mrinal Joel,Randi G. Syljuåsen +6 more
TL;DR: In this paper, the effects of simultaneous inhibition of WEE1 and ATR kinases were investigated in U2OS osteosarcoma cells and in four lung cancer cell lines, H460, A549, H1975, and SW900.
Journal ArticleDOI
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
TL;DR: It is suggested that degradation of promoter proximal RNAPII plays an unanticipated large role both during normal transcription and after UV, indicating cell cycle specific effects.
Journal ArticleDOI
New link between the RNA polymerase II-CTD and replication stress
TL;DR: The authors showed that proper dephosphorylation of Serine 5 in the carboxy-terminal domain (CTD) of DNA-directed RNA polymerase II subunit RPB1 is needed to prevent conflicts between transcription and replication in human cells.