L
Linda E. Hyman
Researcher at Boston University
Publications - 30
Citations - 2029
Linda E. Hyman is an academic researcher from Boston University. The author has contributed to research in topics: Saccharomyces cerevisiae & Transcription (biology). The author has an hindex of 16, co-authored 30 publications receiving 1900 citations. Previous affiliations of Linda E. Hyman include Tulane University & Montana State University.
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Journal ArticleDOI
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
TL;DR: Recent findings suggest that the association of cleavage/polyadenylation factors with the transcriptional complex via the carboxyl-terminal domain of the RNA polymerase II (Pol II) large subunit is the means by which the cell restricts polyadenylations to Pol II transcripts.
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Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae.
TL;DR: The pBEVY plasmids were designed with constitutive and galactose-induced bi-directional promoters to direct the expression of multiple proteins in Saccharomyces cerevisiae as discussed by the authors.
Journal ArticleDOI
Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation
Linda E. Hyman,W M Wormington +1 more
TL;DR: The proper translational regulation of an exogenous ribosomal protein mRNA in microinjected oocytes provides a basis for determining the sequence specificity for the differential utilization of maternal mRNAs during oocyte maturation.
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Effects of low-shear modeled microgravity on cell function, gene expression, and phenotype in Saccharomyces cerevisiae.
TL;DR: Low-shear environments may significantly alter yeast gene expression and phenotype as well as evolutionary conserved cellular functions such as polarization, providing a paradigm for understanding polarity-dependent cell responses to microgravity ranging from pathogenesis in fungi to the immune response in mammals.
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Spaceflight Enhances Cell Aggregation and Random Budding in Candida albicans
Aurélie Crabbé,Sheila M. Nielsen-Preiss,Christine M. Woolley,Jennifer Barrila,Kent L. Buchanan,Kent L. Buchanan,James McCracken,James McCracken,Diane O. Inglis,Stephen C. Searles,Mayra Nelman-Gonzalez,C. Mark Ott,James W. Wilson,James W. Wilson,James W. Wilson,Duane L. Pierson,Heidemarie M. Stefanyshyn-Piper,Linda E. Hyman,Linda E. Hyman,Cheryl A. Nickerson,Cheryl A. Nickerson +20 more
TL;DR: Since the low fluid-shear environment of microgravity is relevant to physical forces encountered by pathogens during the infection process, insights gained from this study could identify novel infectious disease mechanisms, with downstream benefits for the general public.