K
Kent L. Buchanan
Researcher at Tulane University
Publications - 24
Citations - 2481
Kent L. Buchanan is an academic researcher from Tulane University. The author has contributed to research in topics: Cryptococcus neoformans & Immune system. The author has an hindex of 19, co-authored 24 publications receiving 2271 citations. Previous affiliations of Kent L. Buchanan include University of Oklahoma Health Sciences Center & Oklahoma City University.
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Journal ArticleDOI
Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq
James W. Wilson,C. M. Ott,K. Höner zu Bentrup,Rajee Ramamurthy,L. Quick,Steffen Porwollik,Pui Cheng,Michael McClelland,George Tsaprailis,Timothy R. Radabaugh,Andrea M. Hunt,D. Fernandez,Emily G. Richter,Miti Shah,Michelle Kilcoyne,Lokesh Joshi,Mayra Nelman-Gonzalez,S. Hing,Macarena Parra,P. Dumars,Kelly L.L. Norwood,R. Bober,J. Devich,A. Ruggles,Carla Goulart,Mark Rupert,Louis S. Stodieck,Phillip Stafford,L. Catella,Michael J. Schurr,Michael J. Schurr,Kent L. Buchanan,Kent L. Buchanan,Lisa A. Morici,James McCracken,James McCracken,Patricia L. Allen,Patricia L. Allen,C. Baker-Coleman,C. Baker-Coleman,Timothy G. Hammond,Timothy G. Hammond,Jörg Vogel,Randall W. Nelson,Duane L. Pierson,Heidemarie M. Stefanyshyn-Piper,C. A. Nickerson +46 more
TL;DR: Strategies to target Hfq and related regulators could potentially decrease infectious disease risks during space flight missions and provide novel therapeutic options on Earth.
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What Makes Cryptococcus neoformans a Pathogen
TL;DR: This work discusses the current knowledge of the characteristics C. neoformans must possess to enter the host and establish progressive disease: basic growth requirements and virulence factors, such as the polysaccharide capsule.
Journal ArticleDOI
Mechanisms of bacterial pathogenicity
James W. Wilson,Michael J. Schurr,C. L. LeBlanc,Rajee Ramamurthy,Kent L. Buchanan,Cheryl A. Nickerson +5 more
TL;DR: The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward the identification and characterisation of all these different strategies for bacterial disease.
Journal ArticleDOI
Introns and Splicing Elements of Five Diverse Fungi
Doris M. Kupfer,Scott D. Drabenstot,Kent L. Buchanan,Hongshing Lai,Hua Zhu,David W. Dyer,Bruce A. Roe,Juneann W. Murphy +7 more
TL;DR: The observations imply that splicing in fungi may be different from that in vertebrates and may require additional proteins that interact with polypyrimidine tracts upstream of the branch point to function.
Journal ArticleDOI
A549 Lung Epithelial Cells Grown as Three-Dimensional Aggregates: Alternative Tissue Culture Model for Pseudomonas aeruginosa Pathogenesis
Alexander J. Carterson,K. Höner zu Bentrup,C. M. Ott,Mark S. F. Clarke,Duane L. Pierson,Charles R. Vanderburg,Kent L. Buchanan,Cheryl A. Nickerson,Michael J. Schurr +8 more
TL;DR: Findings suggest that A549 lung cells grown as 3-D aggregates may represent a more physiologically relevant model to examine the interactions between P. aeruginosa and the lung epithelium during infection.