L
Long Duc Nguyen
Researcher at Charité
Publications - 4
Citations - 307
Long Duc Nguyen is an academic researcher from Charité. The author has contributed to research in topics: N-Acetylneuraminic acid & N-Acetylmannosamine. The author has an hindex of 4, co-authored 4 publications receiving 274 citations.
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Journal ArticleDOI
Two‐Color Glycan Labeling of Live Cells by a Combination of Diels–Alder and Click Chemistry
Andrea Niederwieser,Anne-Katrin Späte,Long Duc Nguyen,Christian Jüngst,Werner Reutter,Valentin Wittmann +5 more
TL;DR: This work shows that ManNAc derivatives containing a terminal alkene in the acyl side chain are metabolically incorporated into cell-surface sialic acids and can subsequently be labeled by the DARinv, and identifies monosubstituted (terminal) alkenes as a new class of chemical reporters.
Journal ArticleDOI
GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response.
Jingsong Zhang,Qingjiu Tang,Changyan Zhou,Wei Jia,Luis Da Silva,Long Duc Nguyen,Werner Reutter,Hua Fan +7 more
TL;DR: Results indicate that GLIS exhibits a capacity to increase remarkably both humoral and cellular immune activities of tumour-bearing mice and inhibits tumour growth significantly.
Journal ArticleDOI
Zweifarbenmarkierung von Glycanen lebender Zellen durch Kombination von Diels‐Alder‐ und Klick‐Chemie
Andrea Niederwieser,Anne-Katrin Späte,Long Duc Nguyen,Christian Jüngst,Werner Reutter,Valentin Wittmann +5 more
Journal ArticleDOI
Crystal Structures of N-Acetylmannosamine Kinase Provide Insights into Enzyme Activity and Inhibition
Jacobo Martinez,Long Duc Nguyen,Stephan Hinderlich,Reinhold Zimmer,Eva Tauberger,Werner Reutter,Wolfram Saenger,Hua Fan,Sebastien Moniot +8 more
TL;DR: A novel inhibitor is synthesized, 6-O-acetyl-ManNAc, which is more potent than those previously tested and serves as a structural basis to design inhibitors of sialic acid biosynthesis.