Lorin S. Milescu

TL;DR: It is concluded that raphé 5-HT neurons excite key circuit components required for generation of respiratory motor output in neonatal and juvenile rats, and can transform the electrophysiological phenotype of some pre-BötC neurons to intrinsic bursters, providing 5- HT with an additional role in promoting rhythm generation.

TL;DR: The algorithm is faster than a recent method that uses the full autocovariance matrix (Celentano and Hawkes, 2004), in part due to the analytical calculation of the likelihood gradients.

TL;DR: A new technique for modeling the kinetics of voltage-gated ion channels in a functional context, in neurons or other excitable cells, on the basis of a computational model that explains both the observed cellular dynamics and the biophysical properties of the channel.

TL;DR: The results suggest that differences in BK channel expression may underlie the differences in electrical activity and basal hormone secretion levels among pituitary cell types and that the rapid rate of BKChannel activation is key to its role in burst promotion.

TL;DR: After 3 decades of controversial reports on the use of thermal imaging in the diagnosis of breast cancer, the authors have shown that dynamic infrared imaging, using a plausible pathophysiological model and up-to-date infrared equipment, can distinguish between noncancerous and cancerous breasts with a highly impressive sensitivity and specificity.