Lorraine F. Meisner

TL;DR: It is suggested that increased dosage of chromosome 17q and 12 gene(s) provides a selective advantage for the propagation of undifferentiated hES cells in transplantation therapies in which the use of aneuploid cells could be detrimental.

TL;DR: A new stem-cell line was derived from human embryos under completely cell and serum free conditions, eliminating exposure of human embryonic stem cells and their progeny to animal and human feeder layers, and thus the risk of contamination with pathogenic agents capable of transmitting diseases to patients.

TL;DR: The impact of TRIPS on either the commercial strategies of foreign companies or their strategic alliances with Indian companies is anyone’s guess, as it is only one parameter among many that will be used in making foreign investment decisions.

TL;DR: This work reports an alternative method of establishing ES cell lines—using a technique of single-cell embryo biopsy similar to that used in pre-implantation genetic diagnosis of genetic defects—that does not interfere with the developmental potential of embryos.

TL;DR: The findings with the NIKS cells support the observation that spontaneous immortalization is not linked to alterations in squamous differentiation or the ability to undergo apoptosis, and is an important new tool for the study of growth and differentiation in stratified squamous epithelia.