L
Lucas S. Ribeiro
Researcher at Universidade Federal de Minas Gerais
Publications - 23
Citations - 667
Lucas S. Ribeiro is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Inflammation & Inflammasome. The author has an hindex of 13, co-authored 21 publications receiving 438 citations. Previous affiliations of Lucas S. Ribeiro include University of Bonn & Universidade Federal do Espírito Santo.
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Journal ArticleDOI
Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum
Irene Bosch,Irene Bosch,Helena de Puig,Megan Hiley,Marc Carré-Camps,Federico Perdomo-Celis,Carlos F. Narváez,Doris M. Salgado,Dewahar Senthoor,Madeline O’Grady,Elizabeth J. Phillips,Ann Durbin,Ann Durbin,Diana Fandos,Hikaru Miyazaki,Chun-Wan Yen,Margarita Gélvez-Ramírez,Rajas V. Warke,Lucas S. Ribeiro,Mauro M. Teixeira,Roque P. Almeida,José Esteban Muñoz-Medina,Juan E. Ludert,Maurício Lacerda Nogueira,Tatiana Elias Colombo,Ana Carolina Bernardes Terzian,Patrícia T. Bozza,Andrea Surrage Calheiros,Yasmine Rangel Vieira,Giselle Barbosa-Lima,Alexandre Gomes Vizzoni,José Cerbino-Neto,Fernando A. Bozza,Thiago Moreno L. Souza,Monique R.O. Trugilho,Ana Maria Bispo de Filippis,Patrícia Carvalho de Sequeira,Ernesto T. A. Marques,Ernesto T. A. Marques,Tereza Magalhaes,Tereza Magalhaes,Francisco J. Díaz,Berta Nelly Restrepo,Katerine Marín,Salim Mattar,Daniel G. Olson,Edwin J. Asturias,Mark Lucera,Mohit Singla,Guruprasad R. Medigeshi,Norma de Bosch,Justina O. Tam,Jose Gomez-Marquez,Charles R. Clavet,Luis Angel Villar,Kimberly Hamad-Schifferli,Kimberly Hamad-Schifferli,Lee Gehrke,Lee Gehrke +58 more
TL;DR: The characterization of monoclonal antibody pairs that have been translated into rapid immunochromatography tests to specifically detect the viral nonstructural 1 (NS1) protein antigen and distinguish the four DENV serotypes (DENV1–4) and ZIKV without cross-reaction are reported.
Journal ArticleDOI
Platelets Fuel the Inflammasome Activation of Innate Immune Cells
Verena Rolfes,Lucas S. Ribeiro,Ibrahim Hawwari,Lisa Böttcher,Nathalia Rosero,Salie Maasewerd,Marina L. S. Santos,Tomasz Próchnicki,Camila Meirelles de Souza Silva,Carlos W. S. Wanderley,Maximilian Rothe,Susanne Schmidt,H. James Stunden,Damien Bertheloot,Magali Noval Rivas,Cor Jesus Fernandes Fontes,Luzia H. Carvalho,Fernando Q. Cunha,Eicke Latz,Eicke Latz,Eicke Latz,Moshe Arditi,Bernardo S. Franklin +22 more
TL;DR: It is shown that platelets boost the inflammasome capacity of human macrophages and neutrophils and are critical for IL-1 production by monocytes and an enriched platelet gene signature among the highest-expressed transcripts in IL- 1β-driven autoinflammatory diseases is revealed.
Journal ArticleDOI
N-Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection.
Vivian Vasconcelos Costa,Juliana L. Del Sarto,Rebeca Rocha,Flavia Rodrigues da Silva,Juliana G. Doria,Isabella G. Olmo,Rafael Elias Marques,Celso Martins Queiroz-Junior,Giselle Foureaux,Julia Maria S. Araújo,Allysson Cramer,Ana Luiza C. V. Real,Lucas S. Ribeiro,Silvia Ines Sardi,Anderson J. Ferreira,Fabiana S. Machado,Antonio C. de Oliveira,Antônio Lúcio Teixeira,Helder I. Nakaya,Danielle G. Souza,Fabiola M. Ribeiro,Mauro M. Teixeira +21 more
TL;DR: The results indicate that the blockade of NMDARs by memantine provides potent neuroprotective effects against ZikV-induced neuronal damage, suggesting it could be a viable treatment for patients at risk for ZIKV infection-induced neurodegeneration.
Journal ArticleDOI
Regulation of Innate Immune Responses by Platelets.
TL;DR: The role of platelets has been extensively studied in the context of coagulation and vascular integrity as mentioned in this paper, which can lead to known conditions such as atherosclerotic plaques, thrombosis, and ischemia.
Posted ContentDOI
Platelets fuel the inflammasome activation of innate immune cells
Verena Rolfes,Lucas S. Ribeiro,Ibrahim Hawwari,Lisa Böttcher,Nathalia Rosero,Salie Maasewerd,Marina L. S. Santos,Susanne V. Schmidt,Maximilian Rothe,H. James Stunden,Luzia H. Carvalho,Cor Jesus Fernandes Fontes,Moshe Arditi,Eicke Latz,Eicke Latz,Eicke Latz,Bernardo S. Franklin +16 more
TL;DR: It is shown that platelets, the second most abundant cells in the blood, boost the inflammasome capacity of human macrophages and neutrophils, and are critical for IL-1 production by monocytes, and that platelet provide an additional layer of regulation ofinflammasomes in vivo.