Lucien T. Thompson

TL;DR: It now appears possible to identify these circuits, localize the sites of memory storage, and analyze the cellular and molecular mechanisms of memory.

TL;DR: Time-dependent, learning-related changes in hippocampal excitability were evaluated by recording from rabbit CA1 pyramidal neurons in slices prepared at various times after acquisition of trace eyeblink conditioning, suggesting a critical window during which learning-specific alterations in postsynaptic excitability of hippocampal neurons are important for consolidation of the learned association elsewhere in the brain.

TL;DR: The present study shows that hippocampal neurons have stable place-field correlates that persist over very long periods of time, indicating that stability of neuronal activity may be as important as plasticity in the integrated processing of information that occurs in the hippocampus and throughout the nervous system.

TL;DR: In complex information processing, such as the processing of spatial information by the hippocampus demonstrated here, neural silence may be as important a signal as neural activity.

TL;DR: In this article, the effects of dihydropyridine L-type calcium channel antagonist nimodipine on aging and young rabbit hippocampal CA1 pyramidal cells in vitro were investigated.