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Luisa Schreyer
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 5
Citations - 3131
Luisa Schreyer is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Circular RNA & microRNA. The author has an hindex of 5, co-authored 5 publications receiving 2319 citations.
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Journal ArticleDOI
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
Agnieszka Rybak-Wolf,Christin Stottmeister,Petar Glažar,Marvin Jens,Natalia S. Pino,Sebastian A. Giusti,Mor Hanan,Mikaela Behm,Osnat Bartok,Reut Ashwal-Fluss,Margareta Herzog,Luisa Schreyer,Panagiotis Papavasileiou,Andranik Ivanov,Marie Öhman,Damian Refojo,Sebastian Kadener,Nikolaus Rajewsky +17 more
TL;DR: A circRNA brain expression atlas and evidence for important circRNA functions and values as biomarkers are provided and discovered and analyzed thousands of neuronal human and mouse circRNAs.
Journal ArticleDOI
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
Monika Piwecka,Petar Glažar,Luis R. Hernandez-Miranda,Sebastian Memczak,Susanne A. Wolf,Agnieszka Rybak-Wolf,Andrei Filipchyk,Filippos Klironomos,Cledi Alicia Cerda Jara,Pascal Fenske,Thorsten Trimbuch,Vera Zywitza,Mireya Plass,Luisa Schreyer,Salah Ayoub,Christine Kocks,Ralf Kühn,Christian Rosenmund,Carmen Birchmeier,Nikolaus Rajewsky +19 more
TL;DR: It is suggested that neuronal Cdr1as stabilizes or transports miR-7, which in turn represses genes that are early responders to different stimuli, and that CDR1as modulates neuronal activity in the human brain.
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A map of human circular RNAs in clinically relevant tissues
Philipp G. Maass,Petar Glažar,Sebastian Memczak,Gunnar Dittmar,Irene Hollfinger,Luisa Schreyer,Aisha V. Sauer,Okan Toka,Alessandro Aiuti,Friedrich C. Luft,Friedrich C. Luft,Nikolaus Rajewsky +11 more
TL;DR: A circRNA expression resource of 20 human tissues highly relevant to disease-related research is presented and evidence for differential circRNAs expression of genes that are involved in the molecular pathogenesis of both phenotypes is found.
Journal ArticleDOI
Cell fixation and preservation for droplet-based single-cell transcriptomics
Jonathan Alles,Nikos Karaiskos,Samantha D. Praktiknjo,Stefanie Grosswendt,Philipp Wahle,Pierre-Louis Ruffault,Salah Ayoub,Luisa Schreyer,Anastasiya Boltengagen,Carmen Birchmeier,Robert P. Zinzen,Christine Kocks,Nikolaus Rajewsky +12 more
TL;DR: It is expected that the availability of a simple cell fixation method will open up many new opportunities in diverse biological contexts to analyse transcriptional dynamics at single-cell resolution.
Posted ContentDOI
Cell fixation and preservation for droplet-based single-cell transcriptomics
Jonathan Alles,Nikos Karaiskos,Samantha D. Praktiknjo,Stefanie Grosswendt,Philipp Wahle,Pierre-Louis Ruffault,Salah Ayoub,Luisa Schreyer,Anastasiya Boltengagen,Carmen Birchmeier,Robert P. Zinzen,Christine Kocks,Nikolaus Rajewsky +12 more
TL;DR: It is expected that the availability of a simple cell fixation method will open up many new opportunities to quantitatively analyze transcriptional dynamics at single-cell resolution.