L
Lun Jiang
Researcher at Tulane University
Publications - 6
Citations - 3058
Lun Jiang is an academic researcher from Tulane University. The author has contributed to research in topics: Cyclase & Pituitary adenylate cyclase-activating peptide. The author has an hindex of 5, co-authored 6 publications receiving 2965 citations.
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Journal ArticleDOI
Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells
Atsuro Miyata,Akira Arimura,Raymond R. Dahl,Naoto Minamino,Akira Uehara,Lun Jiang,M.D. Culler,David H. Coy +7 more
TL;DR: A novel neuropeptide which stimulates adenylate cyclase in rat anterior pituitary cell cultures was isolated from ovine hypothalamic tissues and increased release of growth hormone, prolactin, corticotropin and luteinizing hormone from superfused rat pituitaries at as small a dose as 10(-10)M) or 10(-9)M (LH).
Journal ArticleDOI
Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38).
Atsuro Miyata,Lun Jiang,Raymond D. Dahl,Chieko Kitada,Kazuki Kubo,Masahiko Fujino,Naoto Minamino,Akira Arimura +7 more
TL;DR: Synthetic PACAP27 which shows a considerable homology with vasoactive intestinal polypeptide (VIP) demonstrated a similar vasodepressor activity as VIP, but the adenylate cyclase stimulating activity was about 1000 times greater than VIP.
Journal ArticleDOI
A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs.
Chiharu Kimura,Shoichi Ohkubo,Kazuhiro Ogi,Masaki Hosoya,Yasuaki Itoh,Haruo Onda,Atsuro Miyata,Lun Jiang,Raymond R. Dahl,Henry H. Stibbs,Akira Arimura,Masahiko Fujino +11 more
TL;DR: Cloning of PACAP38 cDNAs confirms the expression of the corresponding mRNAs and the presence of this neuropeptide in ovine hypothalamus and also in human testis.
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Identification of calcitonin gene related peptide in ovine hypothalamic extract.
TL;DR: Calcitonin gene-related polypeptide was purified from ovine hypothalamic extracts and had adenylate cyclase stimulating activity comparable to corticotropin-releasing hormone, suggesting a hypophysiotropic role for CGRP.
Journal ArticleDOI
Chemical characterization of vasoactive intestinal polypeptide-like immunoreactivity in ovine hypothalamus and intestine.
TL;DR: Amino acid analysis as well as amino acid sequence analysis showed that ovine hypothalamic and intestinal VIP were identical to porcine VIP, but different from PACAP.