L
Lydia Barakat
Researcher at Yale University
Publications - 44
Citations - 853
Lydia Barakat is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 9, co-authored 35 publications receiving 686 citations.
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Journal ArticleDOI
Complicated left-sided native valve endocarditis in Adults: Risk classification for mortality
TL;DR: Adults with complicated left-sided native valve endocarditis can be accurately risk stratified using baseline features into 4 groups of prognostic severity, and this prognostic classification system might be useful for facilitating management decisions.
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Fatal Inhalational Anthrax in a 94-Year-Old Connecticut Woman
Lydia Barakat,Howard L. Quentzel,John A. Jernigan,David Kirschke,Kevin S. Griffith,Stephen M. Spear,Katherine A. Kelley,Diane Barden,Donald R. Mayo,David S. Stephens,Tanja Popovic,Chung K. Marston,Sherif R. Zaki,Jeanette Guarner,Wun-Ju Shieh,H. Wayne Carver,Richard F. Meyer,David L. Swerdlow,Eric E. Mast,James L. Hadler +19 more
TL;DR: The patient's clinical course was characterized by progression of respiratory insufficiency, pleural effusions and pulmonary edema, and, ultimately, death, and viable B anthracis was present in postmortem mediastinal lymph node specimens.
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Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19.
Shelli F. Farhadian,Laura R. Glick,Chantal B.F. Vogels,Jared Thomas,Jennifer Chiarella,Arnau Casanovas-Massana,Jing Zhou,Camila D. Odio,Pavithra Vijayakumar,Bertie Geng,John Fournier,Santos Bermejo,Joseph R. Fauver,Tara Alpert,Anne L. Wyllie,Cynthia Turcotte,Matthew Steinle,Patrick Paczkowski,Charles S. Dela Cruz,Craig B. Wilen,Albert I. Ko,Sean Mackay,Nathan D. Grubaugh,Serena Spudich,Lydia Barakat +24 more
TL;DR: The findings suggest that neurologic symptoms such as encephalopathy and seizures may be the initial presentation of COVID-19, and central nervous system inflammation may associate with neurologic manifestations of disease.
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Antiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition.
Shanmugapriya Selvaraj,Musie Ghebremichael,Min Li,Yram Foli,Allison Langs-Barlow,Arit Ogbuagu,Lydia Barakat,Elizabeth Tubridy,Regina Edifor,Wing Lam,Yung-Chi Cheng,Elijah Paintsil +11 more
TL;DR: Depletion of RN and dRN pools may be associated with ART‐induced mitochondrial toxicity independent of pol‐γ inhibition, and Antiretroviral therapy (ART) perturbs RN anddRN pools.
Journal ArticleDOI
Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers
Wendy E. Walker,Sebastian Kurscheid,Samit R Joshi,Charlie A Lopez,Gerald Goh,Murim Choi,Lydia Barakat,John Francis,Ann Fisher,Maichael J Kozal,Heidi J Zapata,Albert C. Shaw,Richard P. Lifton,Richard E. Sutton,Erol Fikrig +14 more
TL;DR: It is demonstrated that a subgroup of elite controllers possess CD4+ T cells that are specifically resistant to R5-tropic HIV while remaining fully susceptible to X4- Tropic and vesicular stomatitis virus G (VSV-G)-pseudotyped viruses.