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Richard P. Lifton

Researcher at Yale University

Publications -  451
Citations -  72083

Richard P. Lifton is an academic researcher from Yale University. The author has contributed to research in topics: Exome sequencing & Exome. The author has an hindex of 119, co-authored 421 publications receiving 63427 citations. Previous affiliations of Richard P. Lifton include Brigham and Women's Hospital & University of Zurich.

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Genetic studies of body mass index yield new insights for obesity biology

Adam E. Locke, +481 more
TL;DR: This paper conducted a genome-wide association study and meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals.
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De novo mutations revealed by whole-exome sequencing are strongly associated with autism

Stephen Sanders, +29 more
- 10 May 2012 - 
TL;DR: It is shown, using whole-exome sequencing of 928 individuals, including 200 phenotypically discordant sibling pairs, that highly disruptive (nonsense and splice-site) de novo mutations in brain-expressed genes are associated with autism spectrum disorders and carry large effects.
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Paul Bastard, +140 more
- 23 Oct 2020 - 
TL;DR: A means by which individuals at highest risk of life-threatening COVID-19 can be identified is identified, and the hypothesis that neutralizing auto-Abs against type I IFNs may underlie critical CO VID-19 is tested.
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Molecular basis of human hypertension: Role of angiotensinogen

Xavier Jeunemaitre, +11 more
- 02 Oct 1992 - 
TL;DR: Evidence of genetic linkage between the angiotensinogen gene (AGT) and hypertension is obtained, association of AGT molecular variants with the disease is demonstrated, and significant differences in plasma concentrations of angiotENSinogen among hypertensive subjects with different AGT genotypes are found.
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Molecular Mechanisms of Human Hypertension

Richard P. Lifton, +3 more
- 23 Feb 2001 - 
TL;DR: Supported in part by a Specialized Center of Research in Hypertension and NIH K08 awards (to A. G. and D. S. G.) and a grant from the Howard Hughes Medical Institute.