Lyle E. Baade

TL;DR: The MATRICS Consensus Cognitive Battery is expected to be the standard tool for assessing cognitive change in clinical trials of cognition-enhancing drugs for schizophrenia and may also aid evaluation of cognitive remediation strategies.

TL;DR: The consensus cognitive battery developed by the National Institute of Mental Health's (NIMH) Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative includes 10 independently developed tests that are recommended as the standard battery for clinical trials of cognitionenhancing interventions for schizophrenia as mentioned in this paper.

TL;DR: This review addresses the question of whether neuropsychological tests can be used to discriminate between cerebral dysfunction and nonorganic psychiatric disorders by considering 94 studies that compared test scores of psychiatric patients with scores of brain-damaged patients or with established norms for organicity.

TL;DR: Overall, caution should be used when utilize the ≤7 cutoff in all clinical groups and when utilizing the ≤6 cutoff in the following groups: cerebrovascular accident, severe memory disorders, mental retardation, borderline intellectual functioning, and English as a second language.

TL;DR: The cognitive profile findings provide a standard to which future studies can compare results from other schizophrenia samples and related disorders; the classification results point to specific areas and levels of cognitive impairment that may advance work rehabilitation efforts.