M
M. Elizabeth Halloran
Researcher at Fred Hutchinson Cancer Research Center
Publications - 270
Citations - 19557
M. Elizabeth Halloran is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Vaccination & Population. The author has an hindex of 56, co-authored 248 publications receiving 15685 citations. Previous affiliations of M. Elizabeth Halloran include University of Washington & Washington University in St. Louis.
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Journal ArticleDOI
Challenges of evaluating and modelling vaccination in emerging infectious diseases
Zachary J. Madewell,Natalie E. Dean,Jesse A. Berlin,Paul Coplan,Kourtney Davis,Claudio J. Struchiner,M. Elizabeth Halloran +6 more
TL;DR: In this article, the authors introduce key challenges for planning, evaluating, and modelling vaccine efficacy trials for emerging pathogens, and introduce mathematical and statistical models to assist investigators in designing infectious disease clinical trials.
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Evaluating the Effectiveness of Vaccines Using a Regression Discontinuity Design.
TL;DR: It is argued that epidemiologic researchers should consider RDDs when evaluating interventions designed to prevent and control diseases, especially those for which randomized clinical trials would present major challenges or be infeasible.
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On the use of state-space models for the evaluation of health interventions
Claudio J. Struchiner,Robert C. Brunet,M. Elizabeth Halloran,Eduardo Massad,R. S. Azevedo-Neto +4 more
TL;DR: A simple transmission model appropriate to evaluate health interventions that confer long term protection and expand on previous statistical procedures to estimate the relevant parameters is discussed.
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Semi-parametric models for mismeasured exposure information in vaccine trials.
TL;DR: Improvements in bias and efficiency are demonstrated when the different levels of exposure information are combined to estimate vaccine efficacy for reducing both susceptibility and infectiousness in an HIV vaccine trial.
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Quantifying the risk of local Zika virus transmission in the contiguous US during the 2015–2016 ZIKV epidemic
Kaiyuan Sun,Qian Zhang,Ana Pastore-Piontti,Matteo Chinazzi,Dina Mistry,Natalie E. Dean,Diana Patricia Rojas,Stefano Merler,Piero Poletti,Luca Rossi,M. Elizabeth Halloran,M. Elizabeth Halloran,Ira M. Longini,Alessandro Vespignani +13 more
TL;DR: A framework for the projection of ZIKV autochthonous transmission in the contiguous US during the 2015–2016 epidemic using a data-driven stochastic and spatial epidemic model accounting for seasonal, environmental, and detailed population data is presented.