M
M. Paz García-Portilla
Researcher at University of Oviedo
Publications - 26
Citations - 710
M. Paz García-Portilla is an academic researcher from University of Oviedo. The author has contributed to research in topics: Population & Schizophrenia. The author has an hindex of 14, co-authored 26 publications receiving 584 citations. Previous affiliations of M. Paz García-Portilla include International Sleep Products Association & Spanish National Research Council.
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Journal ArticleDOI
Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of Psychosis: Toward an Integrative Inflammatory Hypothesis of Schizophrenia
Borja García-Bueno,Miquel Bioque,Karina S. MacDowell,M. Fe Barcones,Mónica Martínez-Cengotitabengoa,Laura Pina-Camacho,Roberto Rodriguez-Jimenez,Pilar A. Saiz,Carmen Castro,Amalia Lafuente,Javier Santabárbara,Ana González-Pinto,Mara Parellada,Gabriel Rubio,M. Paz García-Portilla,Juan Antonio Mico,Miguel Bernardo,Juan C. Leza +17 more
TL;DR: The results of this study indicate robust phenotypical differences at the cellular machinery level in PMBC of patients with FEP, suggesting the anti-inflammatory mediator 15d-PGJ2 might be used as plasmatic biomarker for first episodes of psychosis.
Journal ArticleDOI
A 25-year follow-up of patients admitted to methadone treatment for the first time: mortality and gender differences.
Luis Jiménez-Treviño,Pilar A. Saiz,M. Paz García-Portilla,Eva M. Díaz-Mesa,Fernando Sánchez-Lasheras,Patricia Burón,M. José Casares,Pedro Marina,Eduardo Gutiérrez(,Julio Bobes +9 more
TL;DR: This study confirms the high mortality of heroin addicts even after enrollment in methadone maintenance treatment (MMT), and women who survived the 25-year follow-up were more likely to have stopped using heroin than men.
Journal ArticleDOI
Functional remediation for patients with bipolar II disorder: Improvement of functioning and subsyndromal symptoms $
Brisa Solé,C. Mar Bonnín,Maria Mayoral,Benedikt L. Amann,I. Torres,Ana González-Pinto,Esther Jiménez,José Manuel Crespo,Francesc Colom,Rafael Tabarés-Seisdedos,María Reinares,José Luis Ayuso-Mateos,Sara Soria,M. Paz García-Portilla,Angela Ibáñez,Eduard Vieta,Anabel Martínez-Arán,Carla Torrent +17 more
TL;DR: The results suggest that the FR appears to be effective in improving the overall functional outcome in BPII, as well as in reducing subdepressive symptoms.
Journal ArticleDOI
Evolution of metabolic risk factors over a two-year period in a cohort of first episodes of psychosis.
Miquel Bioque,M. Paz García-Portilla,Clemente Garcia-Rizo,Bibiana Cabrera,Antonio Lobo,Ana González-Pinto,Covadonga M. Díaz-Caneja,Iluminada Corripio,Eduard Vieta,Josefina Castro-Fornieles,Julio Bobes,Miguel Gutiérrez-Fraile,Roberto Rodriguez-Jimenez,Gisela Mezquida,Adrián LLerena,Jerónimo Saiz-Ruiz,Miguel Bernardo +16 more
TL;DR: The results highlight the extremely high risk of patients at early phases of schizophrenia and other psychotic disorders of developing cardiovascular comorbidity and the fast worsening of the metabolic profile during the first two years.
Journal ArticleDOI
Genetic polymorphisms in the dopamine-2 receptor (DRD2), dopamine-3 receptor (DRD3), and dopamine transporter (SLC6A3) genes in schizophrenia: Data from an association study.
Pilar A. Saiz,M. Paz García-Portilla,Celso Arango,Blanca Morales,Bárbara Arias,Paul Corcoran,Juan M. Fernández,Victoria Alvarez,Eliecer Coto,M.T. Bascarán,Manuel Bousoño,Lourdes Fañanás,Julio Bobes +12 more
TL;DR: Evidence is provided that a genetic variant in the DRD2 gene and possible interaction between DRD3 and SLC6A3 genes are associated with schizophrenia and these findings warrant examination in replication studies.