Bibiana Cabrera

TL;DR: Differences in frequency of daily cannabis use and in use of high-potency cannabis contributed to the striking variation in the incidence of psychotic disorder across the 11 studied sites, giving important implications for public health.

TL;DR: The association between white noise speech illusions and familial risk is contingent on additional evidence of endophenotypic expression and of exposure to childhood adversity, and speech illusions may represent a trait-dependent risk marker.

TL;DR: A review of the recent developments and how integrated, large-scale investigations may overcome contemporary challenges in G × E research can be found in this paper, drawing on the example of a large, international, multi-center study into the identification and translational application of gene-environment interactions in schizophrenia.

TL;DR: The results suggest that the etiopathogenesis of schizophrenia involves genetic underpinnings that act by making individuals more sensitive to the effects of some environmental exposures, including cannabis use and exposure to early‐life adversities.

TL;DR: Poorer premorbid adjustment together with socio-demographic factors and higher daily antipsychotic doses were related to a generalized cognitive impairment and to a lowerPremorbid intellectual reserve, suggesting that neurodevelopmental impairment was present before illness onset.