M
Maciej Strak
Researcher at Utrecht University
Publications - 62
Citations - 2555
Maciej Strak is an academic researcher from Utrecht University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 40 publications receiving 1758 citations.
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Journal ArticleDOI
Respiratory Health Effects of Airborne Particulate Matter: The Role of Particle Size, Composition, and Oxidative Potential—The RAPTES Project
Maciej Strak,Nicole A.H. Janssen,Krystal J Godri,Ilse Gosens,Ian Mudway,Flemming R. Cassee,Erik Lebret,Frank J. Kelly,Roy M. Harrison,Bert Brunekreef,Bert Brunekreef,Maaike Steenhof,Gerard Hoek +12 more
TL;DR: Changes in PNC, NO2, and NOx were associated with evidence of acute airway inflammation (i.e., FENO) and impaired lung function and were robust and insensitive to adjustment for other pollutants.
Journal ArticleDOI
In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project
Maaike Steenhof,Ilse Gosens,Maciej Strak,Krystal J Godri,Krystal J Godri,Gerard Hoek,Flemming R. Cassee,Ian Mudway,Frank J. Kelly,Roy M. Harrison,Erik Lebret,Bert Brunekreef,Nicole A.H. Janssen,Raymond Pieters +13 more
TL;DR: The response of RAW264.7 cells to ambient PM was markedly different using samples collected at various sites in the Netherlands that differed in their local PM emission sources, in support of other investigations showing that the chemical composition as well as oxidative potential are determinants of PM induced toxicity in vitro.
Journal ArticleDOI
Oxidative potential of particulate matter collected at sites with different source characteristics
Nicole A.H. Janssen,Aileen Yang,Maciej Strak,Maaike Steenhof,Bryan Hellack,Miriam E. Gerlofs-Nijland,Thomas A. J. Kuhlbusch,Frank J. Kelly,Roy M. Harrison,Roy M. Harrison,Bert Brunekreef,Gerard Hoek,Flemming R. Cassee +12 more
TL;DR: In this article, three a-cellular assays; dithiothreitol (OPDTT), electron spin resonance (OPESR), and ascorbate depletion (OPAA) were used to characterize the oxidative potential (OP) of PM.
Journal ArticleDOI
Respiratory health effects of ultrafine and fine particle exposure in cyclists
Maciej Strak,Hanna Boogaard,Kees Meliefste,Marieke Oldenwening,Moniek Zuurbier,Bert Brunekreef,Gerard Hoek +6 more
TL;DR: Exposure to ultrafine particles and soot during cycling was weakly associated with increased exhaled NO, indicative of airway inflammation, and decrements in lung function 6 h after exposure.
Journal ArticleDOI
Spatial PM2.5, NO2, O3 and BC models for Western Europe - Evaluation of spatiotemporal stability.
Kees de Hoogh,Kees de Hoogh,Jie Chen,John S. Gulliver,Barbara Hoffmann,Ole Hertel,Matthias Ketzel,Mariska Bauwelinck,Aaron van Donkelaar,Ulla Arthur Hvidtfeldt,Klea Katsouyanni,Klea Katsouyanni,Jochem O. Klompmaker,Randal V. Martin,Randal V. Martin,Evangelia Samoli,Per E. Schwartz,Massimo Stafoggia,Tom Bellander,Maciej Strak,Kathrin Wolf,Danielle Vienneau,Danielle Vienneau,Bert Brunekreef,Gerard Hoek +24 more
TL;DR: Kriging proved an efficient technique to explain a part of residual spatial variation for the pollutants with a strong regional component explaining respectively 10%, 24% and 16% of the R2 in the PM2.5, NO2, O3 and BC hybrid LUR models.