M
Magnus Isaksson
Researcher at Uppsala University
Publications - 32
Citations - 1592
Magnus Isaksson is an academic researcher from Uppsala University. The author has contributed to research in topics: Population & Genome. The author has an hindex of 17, co-authored 32 publications receiving 1208 citations. Previous affiliations of Magnus Isaksson include Uppsala University Hospital & Stanford University.
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Journal ArticleDOI
Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.
Nicole L. Washington,Karthik Gangavarapu,Mark Zeller,Alexandre Bolze,Elizabeth T. Cirulli,Kelly M. Schiabor Barrett,Brendan B. Larsen,Catelyn Anderson,Simon R. White,Tyler Cassens,Sharoni Jacobs,Geraint Levan,Jason Nguyen,Jimmy M. Ramirez,Charlotte Rivera-Garcia,Efren Sandoval,Xueqing Wang,David T.W. Wong,Emily Spencer,Refugio Robles-Sikisaka,Ezra Kurzban,Laura D. Hughes,Xianding Deng,Candace Wang,Venice Servellita,Holly Valentine,Peter De Hoff,Phoebe Seaver,Shashank Sathe,Kimberly Gietzen,Brad Sickler,Jay Antico,Kelly Hoon,Jingtao Liu,Aaron Harding,Omid Bakhtar,Tracy Basler,Brett Austin,Duncan MacCannell,Magnus Isaksson,Phillip G. Febbo,David M. Becker,Marc Laurent,Eric McDonald,Gene W. Yeo,Rob Knight,Louise C. Laurent,Eileen de Feo,Michael Worobey,Charles Y. Chiu,Marc A. Suchard,James T. Lu,William E. Lee,Kristian G. Andersen +53 more
TL;DR: In this paper, the authors investigated the prevalence and dynamics of B.1.7 in the United States (US), tracking it back to its early emergence using S gene target failure (SGTF) and SARS-CoV-2 genomic sequencing.
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Duplication of FGF3 , FGF4 , FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs
Nicolette Salmon Hillbertz,Magnus Isaksson,Elinor K. Karlsson,Elinor K. Karlsson,Eva Hellmén,Gerli Pielberg,Peter Savolainen,Claire M. Wade,Claire M. Wade,Henrik von Euler,Ulla Gustafson,Åke Hedhammar,Mats Nilsson,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Leif Andersson,Leif Andersson,Göran Andersson +17 more
TL;DR: The dorsal hair ridge in Rhodesian and Thai Ridgeback dogs is caused by a dominant mutation that also predisposes to the congenital developmental disorder dermoid sinus, and it is shown that the causative mutation is a 133-kb duplication involving three fibroblast growth factor genes.
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Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis
TL;DR: It is demonstrated that TLR4 and TLR9 regulate disease severity in MOG‐induced EAE, and the role of individual TLR and MyD88, the common TLR adaptor molecule, in the initiation of innate and adaptive immune responses in EAE is studied.
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Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE
Magnus Isaksson,Brita Ardesjö,Lars Rönnblom,Olle Kämpe,Hans Lassmann,Maija-Leena Eloranta,Anna Lobell +6 more
TL;DR: It is demonstrated that pDC promote initiation of MOG‐induced Th17‐cell responses and EAE, and only a minor part of the EAE‐promoting effect of pDC appears to be mediated by IFN‐α/β secretion.
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Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts.
Elizabeth T. Cirulli,Simon R. White,Robert W Read,Gai Elhanan,William J. Metcalf,Francisco Tanudjaja,Donna M. Fath,Efren Sandoval,Magnus Isaksson,Karen Schlauch,Joseph J. Grzymski,James T. Lu,Nicole L. Washington +12 more
TL;DR: Cirulli et al. as discussed by the authors analyzed rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK Biobank and 34 phenotypes (1821 overlapping with UK biobank) in 21,866 members of the Healthy Nevada Project (HNP) cohort who underwent Exome-+-sequencing at Helix.