M
Mahvash Tavassoli
Researcher at King's College London
Publications - 82
Citations - 3987
Mahvash Tavassoli is an academic researcher from King's College London. The author has contributed to research in topics: Cancer & Head and neck squamous-cell carcinoma. The author has an hindex of 32, co-authored 80 publications receiving 3506 citations. Previous affiliations of Mahvash Tavassoli include University of London & University of Cambridge.
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Journal ArticleDOI
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis.
Daniele Bergamaschi,Milena Gasco,Louise Hiller,Alexandra Sullivan,Nelofer Syed,Giuseppe Trigiante,Isik G. Yulug,Marco Merlano,Gianmauro Numico,Alberto Comino,Marlene Attard,Olivier Reelfs,Barry A. Gusterson,Alexandra K. Bell,Victoria J. Heath,Mahvash Tavassoli,Paul J. Farrell,Paul R. Smith,Xin Lu,Tim Crook +19 more
TL;DR: Polymorphism in p53 may influence individual responsiveness to cancer therapy, and clinical response following cisplatin-based chemo-radiotherapy for advanced head and neck cancer is influenced by this polymorphism, cancers expressing 72R mutants having lower response rates than those expressing 72P mutants.
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Clinical update on head and neck cancer: molecular biology and ongoing challenges.
E. Alsahafi,Katheryn Begg,Ivano Amelio,Nina Raulf,Philippe Lucarelli,Thomas Sauter,Mahvash Tavassoli +6 more
TL;DR: This update aims to build on the earlier 2014 review by bringing up to date the understanding of the molecular biology of HNSCCs and provide insights into areas of ongoing research and perspectives for the future.
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The expression of p185(HER-2/neu) correlates with the stage of disease and survival in colorectal cancer.
Sanja Kapitanović,Senka Radošević,M Kapitanovic,Simun Andelinovic,Z Ferencic,Mahvash Tavassoli,Dragan Primorac,Zdenko Sonicki,Šime Spaventi,Krešimir Pavelić,Radan Spaventi +10 more
TL;DR: The p185(HER-2/neu) rate expression could serve as an independent prognostic factor in patients with p185-positive colorectal malignancies and show significant correlation with the epithelial abnormality degree and clinical parameters.
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Clinical update on cancer: molecular oncology of head and neck cancer
TL;DR: This clinical update aims to provide an insight into the current understanding of the molecular pathogenesis of the disease, and explores the novel therapies under development and in clinical trials.
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Molecular markers in oral epithelial dysplasia: review
Gayani N. Pitiyage,Wanninayake Mudiyanselage Tilakaratne,Mahvash Tavassoli,Saman Warnakulasuriya +3 more
TL;DR: It is clear from the large number of studies that multiple genes/pathways are involved in the progression from normal to metaplastic/dysplastic, and subsequently to cancer, and it is necessary to study those significant alterations in multiple genes simultaneously in biopsy samples from large cohorts of subjects.