M
Majid Mehtali
Researcher at French Institute of Health and Medical Research
Publications - 4
Citations - 249
Majid Mehtali is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transgene & Genetically modified mouse. The author has an hindex of 4, co-authored 4 publications receiving 248 citations. Previous affiliations of Majid Mehtali include Transgene SA.
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A ubiquitous mammalian expression vector, pHMG, based on a housekeeping gene promoter.
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The methylation-free status of a housekeeping transgene is lost at high copy number
TL;DR: Loss of hypomethylation at high copy number may indicate that saturable DNA-binding factors normally protect the HMGCR promoter from methylation.
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Breast cancer protein PS2 synthesis in mammary gland of transgenic mice and secretion into milk.
Catherine Tomasetto,Catherine Wolf,Marie-Christine Rio,Majid Mehtali,Marianne LeMeur,Pierre Gerlinger,Pierre Chambon,Richard Lathe +7 more
TL;DR: Transgenic mice bearing fusion constructs designed to direct the expression of human PS2 in the lactating mammary gland under the control of the whey acidic protein (WAP) promoter failed to express the transgene, and PS2 expression had no discernable effect upon the physiology and/or development of the suckling young or the transgenic mother.
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Precocious mammary gland development and milk protein synthesis in transgenic mice ubiquitously expressing human growth hormone.
O. Bchini,A.C. Andres,B. Schubaur,Majid Mehtali,Marianne LeMeur,Richard Lathe,Pierre Gerlinger +6 more
TL;DR: The effect of hGH on mammary differentiation does not appear to be solely mediated through an interaction with PRL receptors, since PRL, when added to cultured mammary tissues, did not elicit an equivalent response.