M
Makoto Arai
Researcher at Chiba University
Publications - 8
Citations - 285
Makoto Arai is an academic researcher from Chiba University. The author has contributed to research in topics: Gene expression & Regulation of gene expression. The author has an hindex of 7, co-authored 8 publications receiving 247 citations.
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Journal ArticleDOI
Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma.
Yuichi Hirasawa,Makoto Arai,Fumio Imazeki,Motohisa Tada,Rintaro Mikata,Kenichi Fukai,Masaru Miyazaki,Takenori Ochiai,Hiromitsu Saisho,Osamu Yokosuka +9 more
TL;DR: CAV1 and CSRP1 were inactivated in HCC by aberrant methylation and they may serve as important biomarkers of malignancy.
Journal ArticleDOI
Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia: a prospective comparative study.
Yuzo Sakai,Reiko Eto,Junji Kasanuki,Fukuo Kondo,Kazuki Kato,Makoto Arai,Takuto Suzuki,Michiko Kobayashi,Tomoaki Matsumura,Dan Bekku,Kenichi Ito,Shingo Nakamoto,Takeshi Tanaka,Osamu Yokosuka +13 more
TL;DR: The diagnostic performance of chromoendoscopy with indigo carmine dye added to acetic acid was significantly greater than that of any of the other modalities and the applicability of this method for gastric neoplasia merits further investigation.
Journal ArticleDOI
Efficacy of combination therapy of antiviral and immunosuppressive drugs for the treatment of severe acute exacerbation of chronic hepatitis B
Keiichi Fujiwara,Shin Yasui,Yutaka Yonemitsu,Kenichi Fukai,Makoto Arai,Fumio Imazeki,Akihiro Suzuki,Hiroshi Suzuki,Tomohito Sadahiro,Shigeto Oda,Osamu Yokosuka +10 more
TL;DR: The early introduction of sufficient doses of corticosteroids and nucleoside analogs could be one option for reversing the potential deterioration of patients with clinically severe, life-threatening exacerbation of chronic hepatitis B.
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Water-assisted colonoscopy: an international modified Delphi review on definitions and practice recommendations.
Sergio Cadoni,Sauid Ishaq,Cesare Hassan,Přemysl Falt,Lorenzo Fuccio,Keith Siau,Joseph Leung,John Anderson,Kenneth F. Binmoeller,Franco Radaelli,Matthew D. Rutter,Matthew D. Rutter,Shinya Sugimoto,Humayun Muhammad,Pradeep Bhandari,Peter V. Draganov,Piet C. de Groen,Andrew Y. Wang,Andrew W. Yen,Chris M. Hamerski,Henrik Thorlacius,Helmut Neumann,Francisco C. Ramirez,Chris J. J. Mulder,Eduardo Albéniz,Arnaldo Amato,Makoto Arai,Adrian Bak,Maximilien Barret,Putut Bayupurnama,Ramsey Cheung,Hey Long Ching,Hartley Cohen,Sunil Dolwani,Shai Friedland,Hideaki Harada,Yu Hsi Hsieh,Bu Hayee,Toshio Kuwai,Vicente Lorenzo-Zúñiga,Mauro Liggi,Takeshi Mizukami,Donatella Mura,David Nylander,Snorri Olafsson,Silvia Paggi,Yanglin Pan,Adolfo Parra-Blanco,Rupert Ransford,J. Rodríguez-Sánchez,Hakan Senturk,N Suzuki,Chih-Wei Tseng,H Uchima,Noriya Uedo,Felix W. Leung +55 more
TL;DR: A modified Delphi consensus among experienced colonoscopists on definitions and practice of WI, THE AUTHORS and UWR is conducted, showing that WI and THEY are not the same in implementation and outcomes.
Journal ArticleDOI
Two-peaked Synchronization in Day/Night Expression Rhythms of the Fibrinogen Gene Cluster in the Mouse Liver *
Eiko Sakao,Akinori Ishihara,Kazumasa Horikawa,Masashi Akiyama,Makoto Arai,Masaki Kato,Naohiko Seki,Kohji Fukunaga,Atsuko Shimizu-Yabe,Katsuro Iwase,Satoko Ohtsuka,Takeyuki Sato,Yoichi Kohno,Shigenobu Shibata,Masaki Takiguchi +14 more
TL;DR: The fibrinogen gene locus provides a unique system for the study of two-peaked day/night rhythms of gene expression in a synchronized form and a number of sequence elements resembling circadian transcription factor-binding sites were found.