M
Malvyne Rolli-Derkinderen
Researcher at French Institute of Health and Medical Research
Publications - 42
Citations - 1728
Malvyne Rolli-Derkinderen is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & RHOA. The author has an hindex of 19, co-authored 29 publications receiving 1496 citations. Previous affiliations of Malvyne Rolli-Derkinderen include University of Nantes.
Papers
More filters
Journal ArticleDOI
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure
Christophe Guilluy,Christophe Guilluy,Jérémy Brégeon,Jérémy Brégeon,Gilles Toumaniantz,Gilles Toumaniantz,Malvyne Rolli-Derkinderen,Malvyne Rolli-Derkinderen,Kevin Retailleau,Laurent Loufrani,Daniel Henrion,Elizabeth Scalbert,Antoine Bril,Raul M. Torres,Stephan Offermanns,Pierre Pacaud,Pierre Pacaud,Gervaise Loirand,Gervaise Loirand +18 more
TL;DR: Evidence is provided that Arhgef1 is the RhoA guanine exchange factor specifically responsible for angiotensin II–induced activation of RHoA signaling in arterial smooth muscle cells and identifies Arh gef1 as a potential target for the treatment of hypertension.
Journal ArticleDOI
RhoA Expression Is Controlled by Nitric Oxide through cGMP-dependent Protein Kinase Activation
TL;DR: In vitro and in vivo results show that NO/PKG signaling positively controls RhoA expression and suggest that the basal release of NO is necessary to maintain RhoB expression and RHoA-dependent functions in vascular smooth muscle cells.
Journal ArticleDOI
Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells
Malvyne Rolli-Derkinderen,Vincent Sauzeau,Laurent Boyer,Emmanuel Lemichez,Céline Baron,Daniel Henrion,Gervaise Loirand,Pierre Pacaud +7 more
TL;DR: It is suggested that Ser188 phosphorylation-mediated protection against degradation is a physiological process regulating the level of endogenous RhoA and define a novel function for RhoGDI, as an inhibitor of Rho protein degradation.
Journal ArticleDOI
Enteric GFAP expression and phosphorylation in Parkinson's disease.
Thomas Clairembault,Thomas Clairembault,Willem Kamphuis,Laurène Leclair-Visonneau,Laurène Leclair-Visonneau,Malvyne Rolli-Derkinderen,Malvyne Rolli-Derkinderen,Emmanuel Coron,Michel Neunlist,Michel Neunlist,Elly M. Hol,Elly M. Hol,Elly M. Hol,Pascal Derkinderen,Pascal Derkinderen +14 more
TL;DR: Evidence is provided that enteric glial reaction occurs in Parkinson's disease and the role of the enteric nervous system in the initiation and/or the progression of the disease is reinforced.
Journal ArticleDOI
Enteric Glial Cells: Recent Developments and Future Directions
Michel Neunlist,Michel Neunlist,Malvyne Rolli-Derkinderen,Malvyne Rolli-Derkinderen,Rocco Latorre,Laurianne Van Landeghem,Laurianne Van Landeghem,Emmanuel Coron,Emmanuel Coron,Pascal Derkinderen,Roberto De Giorgio +10 more
TL;DR: Emerging concepts as to how EGCs regulate neuromediator expression, exert neuroprotective roles, and even act as neuronal as well as glial progenitors in the enteric nervous system are summarized.