M
Manabu Ishida
Researcher at Nagaoka University of Technology
Publications - 2
Citations - 145
Manabu Ishida is an academic researcher from Nagaoka University of Technology. The author has contributed to research in topics: Fluorophore & BODIPY. The author has an hindex of 2, co-authored 2 publications receiving 107 citations.
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Journal ArticleDOI
Hoechst tagging: a modular strategy to design synthetic fluorescent probes for live-cell nucleus imaging
Akinobu Nakamura,Kazumasa Takigawa,Yasutaka Kurishita,Keiko Kuwata,Manabu Ishida,Yasushi Shimoda,Itaru Hamachi,Shinya Tsukiji +7 more
TL;DR: This work reports a general strategy to create small-molecule fluorescent probes for the nucleus in living cells based on the attachment of the DNA-binding Hoechst compound to a fluorophore of interest.
Journal ArticleDOI
Synthetic Self-Localizing Ligands That Control the Spatial Location of Proteins in Living Cells
Manabu Ishida,Hideaki Watanabe,Kazumasa Takigawa,Yasutaka Kurishita,Choji Oki,Akinobu Nakamura,Itaru Hamachi,Shinya Tsukiji +7 more
TL;DR: It is shown that SLLs bind their target proteins and relocate (tether) them rapidly from the cytoplasm to their targeting sites, thus serving as synthetic protein translocators, thus opening a new direction in the design of small-molecule tools or drugs for cell regulation.