M
Marc Clement
Researcher at University of Cambridge
Publications - 46
Citations - 2251
Marc Clement is an academic researcher from University of Cambridge. The author has contributed to research in topics: Inflammation & Immune system. The author has an hindex of 21, co-authored 42 publications receiving 1675 citations. Previous affiliations of Marc Clement include Sorbonne & French Institute of Health and Medical Research.
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Journal ArticleDOI
Macrophage Plasticity in Experimental Atherosclerosis
Jamila Khallou-Laschet,Aditi Varthaman,Giulia Fornasa,Caroline Compain,Anh Thu Gaston,Marc Clement,Michael Dussiot,Olivier Levillain,Stéphanie Graff-Dubois,Stéphanie Graff-Dubois,Antonino Nicoletti,Giuseppina Caligiuri +11 more
TL;DR: The study suggests that interventional tools able to revert the MØ infiltrate towards the M2 phenotype may exert an atheroprotective action.
Journal ArticleDOI
Monocytes and macrophages in abdominal aortic aneurysm.
Juliette Raffort,Fabien Lareyre,Fabien Lareyre,Marc Clement,Réda Hassen-Khodja,Giulia Chinetti,Ziad Mallat,Ziad Mallat +7 more
TL;DR: It is shown and proposed that distinct monocyte and macrophage subsets have critical and differential roles in initiation, progression, and healing of the aneurysmal process.
Journal ArticleDOI
Control of the T Follicular Helper–Germinal Center B-Cell Axis by CD8+ Regulatory T Cells Limits Atherosclerosis and Tertiary Lymphoid Organ Development
Marc Clement,Kevin Guedj,Francesco Andreata,Marion Morvan,Laetitia Bey,Jamila Khallou-Laschet,Anh-Thu Gaston,Sandrine Delbosc,Jean-Marc Alsac,Patrick Bruneval,Catherine Deschildre,Marie Le Borgne,Yves Castier,Hye-Jung Kim,Harvey Cantor,Jean-Baptiste Michel,Giuseppina Caligiuri,Antonino Nicoletti +17 more
TL;DR: In this article, the authors analyzed the contribution of Qa-1-restricted CD8+ regulatory T cells to the control of the T follicular helper-germinal center B-cell axis during atherogenesis.
Journal ArticleDOI
An immunologist's guide to CD31 function in T-cells.
TL;DR: Recent findings that have brought to light a non-redundant, complex role for this molecule in the regulation of T-cell-mediated immune responses, with large impact on the understanding of immunity in health and disease are discussed.
Journal ArticleDOI
Diabetes and aortic aneurysm: current state of the art.
Juliette Raffort,Fabien Lareyre,Fabien Lareyre,Marc Clement,Réda Hassen-Khodja,Giulia Chinetti,Ziad Mallat,Ziad Mallat +7 more
TL;DR: Current knowledge on the relationship between glycaemic parameters, diabetes, and the development of aortic aneurysm is summarized and a large body of evidence points to an inverse association between diabetes and both AAA and TAA.