M
Marc Edery
Researcher at Centre national de la recherche scientifique
Publications - 70
Citations - 7407
Marc Edery is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Prolactin receptor & Receptor. The author has an hindex of 35, co-authored 70 publications receiving 7136 citations. Previous affiliations of Marc Edery include University of Paris & French Institute of Health and Medical Research.
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Journal ArticleDOI
Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice
TL;DR: It is clear that there are multiple actions associated with PRL, and the technique of gene targeting in mice has been used to develop the first experimental model in which the effect of the complete absence of any lactogen or PRL-mediated effects can be studied.
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The prolactin/growth hormone receptor family.
TL;DR: It is doubtful that one unifying mechanism of action will be found for this hormone, as several potential components of the signal transduction pathways have been identified, but as yet none has clearly been shown to be able to mimic the effect of PRL or GH.
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Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.
Christopher J. Ormandy,A Camus,J. Barra,Diane Damotte,B. Lucas,Hélène Buteau,Marc Edery,Nicole Brousse,Charles Babinet,Nadine Binart,Paul A. Kelly +10 more
TL;DR: This work establishes the prolactin receptor as a key regulator of mammalian reproduction, and provides the first total ablation model to further study the role of the prolACTin receptor and its ligands.
Journal ArticleDOI
Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family
Jean-Marie Boutin,Christine Jolicoeur,Hiroaki Okamura,Jean Gagnon,Marc Edery,Mariko Shirota,Denis Banville,Isabelle Dusanter-Fourt,Jean Djiane,Paul A. Kelly +9 more
TL;DR: There is strong localized sequence identity between these two receptors in both the extracellular and cytoplasmic domains, suggesting that the two receptors originated from a common ancestor.
Journal ArticleDOI
Identification of a cDNA Encoding a Long Form of Prolactin Receptor in Human Hepatoma and Breast Cancer Cells
Jean-Marie Boutin,Marc Edery,Mariko Shirota,Christine Jolicoeur,Laurence Lesueur,Suhad Ali,David Gould,Jean Djiane,Paul A. Kelly +8 more
TL;DR: Human PRL receptor cDNA clones from hepatoma and breast cancer libraries were isolated by using a rat PRL receptors cDNA probe to better understand the role of PRL in the development and growth of human breast cancer.